Heavy metal exposure: molecular pathways, clinical implications, and protective strategies

H Koyama, T Kamogashira, T Yamasoba - Antioxidants, 2024 - mdpi.com
Heavy metals are often found in soil and can contaminate drinking water, posing a serious
threat to human health. Molecular pathways and curation therapies for mitigating heavy …

Research progress in use of traditional Chinese medicine for treatment of spinal cord injury

Y Lu, J Yang, X Wang, Z Ma, S Li, Z Liu… - Biomedicine & …, 2020 - Elsevier
Background Spinal cord injury (SCI) is a serious central nervous system disorder caused by
trauma that has gradually become a major challenge in clinical medical research. As an …

Association between Pb, Cd, and Hg exposure and liver injury among Korean adults

DW Kim, J Ock, KW Moon, CH Park - International journal of …, 2021 - mdpi.com
Background: Exposure to lead (Pb), cadmium (Cd), and mercury (Hg) has been reported to
be associated with liver-related diseases. However, studies examining the association …

[HTML][HTML] Vitamin E protects against cadmium-induced sub-chronic liver injury associated with the inhibition of oxidative stress and activation of Nrf2 pathway

J Fang, H Yin, Z Yang, M Tan, F Wang, K Chen… - Ecotoxicology and …, 2021 - Elsevier
Hepatic oxidative stress, as one important mechanism of cadmium (Cd)-induced hepatic
toxicity, could, as known, be ameliorated by vitamin E (VE). However, the underlying …

Protective effect of quercetin on cadmium-induced renal apoptosis through cyt-c/caspase-9/caspase-3 signaling pathway

R Huang, L Ding, Y Ye, K Wang, W Yu, B Yan… - Frontiers in …, 2022 - frontiersin.org
Cadmium (Cd), a heavy metal, has harmful effects on animal and human health, and it can
also obviously induce cell apoptosis. Quercetin (Que) is a flavonoid compound with …

Lycium barbarum polysaccharide protects against oxygen glucose deprivation/reoxygenation-induced apoptosis and autophagic cell death via the PI3K/Akt/mTOR …

Y Yu, X Wu, J Pu, P Luo, W Ma, J Wang, J Wei… - Biochemical and …, 2018 - Elsevier
Lycium barbarum polysaccharide (LBP) is the main active ingredient of Lycium barbarum,
which exhibits several beneficial effects, including neuroprotection, anti-aging and anti …

Polysaccharide from Flammulina velutipes residues protects mice from Pb poisoning by activating Akt/GSK3β/Nrf-2/HO-1 signaling pathway and modulating gut …

Y Liu, H Li, P Ren, Y Che, J Zhou, W Wang… - International journal of …, 2023 - Elsevier
Lead (Pb) can cause damages to the brain, liver, kidney, endocrine and other systems.
Flammulina velutipes residues polysaccharide (FVRP) has been reported to exhibit anti …

Lycium barbarum polysaccharide protects against LPS-induced ARDS by inhibiting apoptosis, oxidative stress, and inflammation in pulmonary endothelial cells

L Chen, W Li, D Qi, D Wang - Free radical research, 2018 - Taylor & Francis
Acute respiratory distress syndrome (ARDS) is a heterogenous syndrome characterised by
diffuse alveolar damage, with an increase in lung endothelial and epithelial permeability …

Lycium barbarum Polysaccharide Extracted from Lycium barbarum Leaves Ameliorates Asthma in Mice by Reducing Inflammation and Modulating Gut Microbiota

F Cui, C Shi, X Zhou, W Wen, X Gao, L Wang… - Journal of medicinal …, 2020 - liebertpub.com
This study was designed to explore the impact of Lycium barbarum polysaccharide (LBP) on
inflammation and gut microbiota in mice with allergic asthma. Mice were divided into four …

Lycium barbarum polysaccharides protects retinal ganglion cells against oxidative stress injury

L Liu, XY Sha, YN Wu, MT Chen… - Neural regeneration …, 2020 - journals.lww.com
The accumulation of excessive reactive oxygen species can exacerbate any injury of retinal
tissue because free radicals can trigger lipid peroxidation, protein damage and DNA …