Major depressive disorder

W Marx, BWJH Penninx, M Solmi… - Nature Reviews …, 2023 - nature.com
Major depressive disorder (MDD) is characterized by persistent depressed mood, loss of
interest or pleasure in previously enjoyable activities, recurrent thoughts of death, and …

Graph-based deep learning for medical diagnosis and analysis: past, present and future

D Ahmedt-Aristizabal, MA Armin, S Denman, C Fookes… - Sensors, 2021 - mdpi.com
With the advances of data-driven machine learning research, a wide variety of prediction
problems have been tackled. It has become critical to explore how machine learning and …

Connectome gradient dysfunction in major depression and its association with gene expression profiles and treatment outcomes

M Xia, J Liu, A Mechelli, X Sun, Q Ma, X Wang… - Molecular …, 2022 - nature.com
Patients with major depressive disorder (MDD) exhibit concurrent deficits in both sensory
and higher-order cognitive processing. Connectome studies have suggested a principal …

Disrupted intrinsic functional brain topology in patients with major depressive disorder

H Yang, X Chen, ZB Chen, L Li, XY Li… - Molecular …, 2021 - nature.com
Aberrant topological organization of whole-brain networks has been inconsistently reported
in studies of patients with major depressive disorder (MDD), reflecting limited sample sizes …

Functional neuroimaging in psychiatry and the case for failing better

MM Nour, Y Liu, RJ Dolan - Neuron, 2022 - cell.com
Psychiatric disorders encompass complex aberrations of cognition and affect and are
among the most debilitating and poorly understood of any medical condition. Current …

[HTML][HTML] Brain correlates of depression, post-traumatic distress, and inflammatory biomarkers in COVID-19 survivors: a multimodal magnetic resonance imaging study

F Benedetti, M Palladini, M Paolini, E Melloni… - Brain, behavior, & …, 2021 - Elsevier
Psychiatric sequelae substantially contribute to the post-acute burden of disease associated
with COVID-19, persisting months after clearance of the virus. Brain imaging shows white …

All roads lead to the default-mode network—global source of DMN abnormalities in major depressive disorder

A Scalabrini, B Vai, S Poletti, S Damiani… - …, 2020 - nature.com
Major depressive disorder (MDD) is a psychiatric disorder characterized by abnormal resting
state functional connectivity (rsFC) in various neural networks and especially in default …

Functional connectivity signatures of major depressive disorder: machine learning analysis of two multicenter neuroimaging studies

S Gallo, A El-Gazzar, P Zhutovsky, RM Thomas… - Molecular …, 2023 - nature.com
The promise of machine learning has fueled the hope for developing diagnostic tools for
psychiatry. Initial studies showed high accuracy for the identification of major depressive …

Statistical power in network neuroscience

K Helwegen, I Libedinsky… - Trends in Cognitive …, 2023 - cell.com
Network neuroscience has emerged as a leading method to study brain connectivity. The
success of these investigations is dependent not only on approaches to accurately map …

ENIGMA MDD: seven years of global neuroimaging studies of major depression through worldwide data sharing

L Schmaal, E Pozzi, T C. Ho, LS Van Velzen… - Translational …, 2020 - nature.com
A key objective in the field of translational psychiatry over the past few decades has been to
identify the brain correlates of major depressive disorder (MDD). Identifying measurable …