[HTML][HTML] The physiology and pharmacology of oxytocin in labor and in the peripartum period

K Uvnäs-Moberg - American journal of obstetrics and gynecology, 2024 - Elsevier
Oxytocin is a reproductive hormone implicated in the process of parturition and widely used
during labor. Oxytocin is produced within the supraoptic nucleus and paraventricular …

Maternal and newborn plasma oxytocin levels in response to maternal synthetic oxytocin administration during labour, birth and postpartum–a systematic review with …

S Buckley, K Uvnäs-Moberg, Z Pajalic… - BMC pregnancy and …, 2023 - Springer
Background The reproductive hormone oxytocin facilitates labour, birth and postpartum
adaptations for women and newborns. Synthetic oxytocin is commonly given to induce or …

Oxytocin: physiology, pharmacology, and clinical application for labor management

AC Hermesch, AS Kernberg, VR Layoun… - American journal of …, 2024 - Elsevier
Oxytocin is a peptide hormone that plays a key role in regulating the female reproductive
system, including during labor and lactation. It is produced primarily in the hypothalamus …

[HTML][HTML] Labor stimulation with oxytocin: effects on obstetrical and neonatal outcomes

P Hidalgo-Lopezosa, M Hidalgo-Maestre… - … latino-americana de …, 2016 - SciELO Brasil
Objective: to evaluate the effects of labor stimulation with oxytocin on maternal and neonatal
outcomes. Method: descriptive and analytical study with 338 women who gave birth at a …

[HTML][HTML] Labor augmentation with oxytocin in low-and lower-middle-income countries: a systematic review and meta-analysis

ML Kujabi, E Mikkelsen, N Housseine, J Obel… - AJOG global reports, 2022 - Elsevier
OBJECTIVE Despite its worldwide use, reviews of oxytocin for labor augmentation include
mainly studies from high-income countries. Meanwhile, oxytocin is a potentially harmful …

Oxytocin receptor DNA methylation is associated with exogenous oxytocin needs during parturition and postpartum hemorrhage

EN Erickson, L Myatt, JS Danoff, KM Krol… - Communications …, 2023 - nature.com
Background The oxytocin receptor gene (OXTR) is regulated, in part, by DNA methylation.
This mechanism has implications for uterine contractility during labor and for prevention or …

Management of spontaneous labour at term in healthy women

L Lee, J Dy, H Azzam - Journal of Obstetrics and Gynaecology Canada, 2016 - Elsevier
Objective The purpose of this guideline is to provide guidance for the intrapartum
management of spontaneous labour, whether normal or abnormal, in term, healthy women …

Examination of the pharmacology of oxytocin and clinical guidelines for use in labor

K Page, WF McCool, M Guidera - Journal of midwifery & …, 2017 - Wiley Online Library
The use of exogenous oxytocin to induce or augment labor has increased in recent years.
This literature‐informed review examines the action of this medication and the potential …

Intrapartum synthetic oxytocin and its effects on maternal well‐being at 2 months postpartum

V Gu, N Feeley, I Gold, B Hayton, S Robins… - Birth, 2016 - Wiley Online Library
Background Synthetic oxytocin (synOT) is commonly used in labor management to induce
and augment labor, and to prevent postpartum hemorrhage. However, its long‐term …

Discontinuing oxytocin infusion in the active phase of labor: a systematic review and meta-analysis

G Saccone, A Ciardulli, JK Baxter… - Obstetrics & …, 2017 - journals.lww.com
OBJECTIVE: To evaluate the benefits and harms of discontinuation of oxytocin after the
active phase of labor is reached. DATA SOURCES: Electronic databases (ie, MEDLINE …