Diabetes mellitus is a main risk factor for periodontitis, but until now, the underlying
molecular mechanisms remain unclear. Diabetes can increase the pathogenicity of the …

Diabetes mellitus is a common systematic chronic disease amongst dental patients. The
elevated glucose microenvironment can prolong the healing of tooth extraction sockets …

Diabetic osteoporosis (DOP) is a metabolic disease which is characterized by impaired
bone microarchitecture and reduced bone mineral density resulting from hyperglycemia …

Osteoporosis (OP) is one of the most common metabolic skeletal disorders and is commonly
seen in the elderly population and postmenopausal women. It is mainly associated with …

Osteoporosis is a prevalent bone disorder characterized by bone mass reduction and
deterioration of bone microarchitecture leading to bone fragility and fracture risk. In recent …

Background Curcumin ameliorates bone loss by inhibiting osteoclastogenesis. Curcumin
inhibits RANKL-promoted autophagy in osteoclast precursors (OCPs), which mediates its …

To assess resolving-like activity by a novel chemically-modified curcumin (CMC2. 24) in a
“two-hit” model of diabetes-associated periodontitis. Macrophages from rats were cultured in …

Osteoporosis is a prevalent bone metabolic disease that poses a significant challenge to
global human health. Jaw osteoporosis, characterized by microstructural damage of the jaw …

Aim To investigate the specific role of arrestin beta‐2 (ARRB2) in the progression of
periodontitis and the underlying mechanisms. Materials and Methods Single‐cell RNA …

Chemically modified curcumin, CMC2. 24, is a promising therapeutic that has shown efficacy
in ameliorating excessive pigmentation in our previous studies. However, its inherent …