Abstract MCL1 (myeloid cell leukemia-1) is a widely recognized pro-survival member of the
Bcl-2 (B-cell lymphoma protein 2) family and a promising target for cancer therapy. While the …

Evading apoptosis has been linked to tumor development and chemoresistance. One
mechanism for this evasion is the overexpression of prosurvival B-cell lymphoma-2 (BCL-2) …

Myeloid cell leukemia‐1 (MCL1), an antiapoptotic member of the BCL2 family characterized
by a short half‐life, functions as a rapid sensor that regulates cell death and other relevant …

As a tripartite cell death switch, B-cell lymphoma protein 2 (Bcl-2) family members precisely
regulate the endogenous apoptosis pathway in response to various cell signal stresses …

Colorectal cancer (CRC) is one of the most common and deadliest forms of cancer. Myeloid
Cell Leukemia 1 (MCL1), a pro-survival member of the Bcl-2 protein family is associated with …

The maturation of RNA from its nascent transcription to ultimate utilization (eg, translation,
miR-mediated RNA silencing, etc.) involves an intricately coordinated series of biochemical …

B-cell lymphoma 2 (Bcl-2) proteins are central, conserved regulators of apoptosis. Bcl-2
family function is regulated by binding interactions between the Bcl-2 homology 3 (BH3) …

Objective Non-platinum chemotherapy is used in platinum resistant/refractory ovarian
cancer patients but offers limited efficacy, especially in those who develop platinum …

Breast cancer (BC) is the most common cancer in women worldwide, and it is one of the
leading causes of cancer death in women. triple-negative breast Cancer (TNBC), a subtype …

Simple Summary This manuscript builds on our recent observations that the cell-death-
suppressing protein, MCL1, is able to directly regulate the DNA damage response …