Therapeutic targeting of noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and
long noncoding RNAs (lncRNAs), represents an attractive approach for the treatment of …

Antibiotic therapy has become increasingly ineffective against bacterial infections due to the
rise of resistance. In particular, ESKAPE pathogens (Enterococcus faecium, Staphylococcus …

Phage therapy is recognized as a promising alternative to antibiotics in treating pulmonary
bacterial infections, however, its use has not been reported for treating secondary bacterial …

Bacteriophages are enigmatic entities that defy definition. Classically, they are specialist
viruses that exclusively parasitize bacterial hosts. Yet this definition becomes limiting when …

Bacterial biofilms formed by pathogens are known to be hundreds of times more resistant to
antimicrobial agents than planktonic cells, making it extremely difficult to cure biofilm-based …

It is increasingly apparent that bacteriophages, viruses that infect bacteria and more
commonly referred to as simply phages, have tropisms outside their bacterial hosts. Using …

Like the sword of Damocles, the threat of a post-antibiotic era is hanging over humanity's
head. The scientific and medical community is thus reconsidering bacteriophage therapy …

Bacteriophages (Phages) are antibacterial viruses that are unaffected by antibiotic drug
resistance. Many Phase I and Phase II phage therapy clinical trials have shown acceptable …

Bacterial resistance against antibiotics is an emergent medical issue. The development of
novel therapeutic approaches is urgently needed and, in this context, bacteriophages …

The increasing global incidence of multidrug-resistant (MDR) bacterial infections threatens
public health and compromises various aspects of modern medicine. Recognising the …