The bioprinting roadmap

W Sun, B Starly, AC Daly, JA Burdick, J Groll… - …, 2020 - iopscience.iop.org
This bioprinting roadmap features salient advances in selected applications of the technique
and highlights the status of current developments and challenges, as well as envisioned …

[HTML][HTML] The role of SOX family members in solid tumours and metastasis

D Grimm, J Bauer, P Wise, M Krüger… - Seminars in cancer …, 2020 - Elsevier
Cancer is a heavy burden for humans across the world with high morbidity and mortality.
Transcription factors including sex determining region Y (SRY)-related high-mobility group …

3D tumor spheroid models for in vitro therapeutic screening: a systematic approach to enhance the biological relevance of data obtained

M Zanoni, F Piccinini, C Arienti, A Zamagni, S Santi… - Scientific reports, 2016 - nature.com
The potential of a spheroid tumor model composed of cells in different proliferative and
metabolic states for the development of new anticancer strategies has been amply …

Update on the effects of microgravity on the musculoskeletal system

OJ Juhl IV, EG Buettmann, MA Friedman… - npj …, 2021 - nature.com
With the reignited push for manned spaceflight and the development of companies focused
on commercializing spaceflight, increased human ventures into space are inevitable …

Magnetic levitational bioassembly of 3D tissue construct in space

VA Parfenov, YD Khesuani, SV Petrov, PA Karalkin… - Science …, 2020 - science.org
Magnetic levitational bioassembly of three-dimensional (3D) tissue constructs represents a
rapidly emerging scaffold-and label-free approach and alternative conceptual advance in …

The impact of microgravity on bone in humans

D Grimm, J Grosse, M Wehland, V Mann, JE Reseland… - Bone, 2016 - Elsevier
Experiencing real weightlessness in space is a dream for many of us who are interested in
space research. Although space traveling fascinates us, it can cause both short-term and …

Accelerated and improved differentiation of retinal organoids from pluripotent stem cells in rotating-wall vessel bioreactors

T DiStefano, HY Chen, C Panebianco, KD Kaya… - Stem cell reports, 2018 - cell.com
Pluripotent stem cells can be differentiated into 3D retinal organoids, with major cell types
self-patterning into a polarized, laminated architecture. In static cultures, organoid …

The cardiovascular system in space: focus on in vivo and in vitro studies

R Baran, S Marchal, S Garcia Campos, E Rehnberg… - Biomedicines, 2021 - mdpi.com
On Earth, humans are subjected to a gravitational force that has been an important
determinant in human evolution and function. During spaceflight, astronauts are subjected to …

Advantages and limitations of current microgravity platforms for space biology research

F Ferranti, M Del Bianco, C Pacelli - Applied Sciences, 2020 - mdpi.com
Human Space exploration has created new challenges and new opportunities for science.
Reaching beyond the Earth's surface has raised the issue of the importance of gravity for the …

Biomanufacturing in low Earth orbit for regenerative medicine

A Sharma, RA Clemens, O Garcia, DL Taylor… - Stem Cell Reports, 2022 - cell.com
Research in low Earth orbit (LEO) has become more accessible. The 2020
Biomanufacturing in Space Symposium reviewed space-based regenerative medicine …