Immunogenic cell death activates the tumor immune microenvironment to boost the immunotherapy efficiency

Z Li, X Lai, S Fu, L Ren, H Cai, H Zhang, Z Gu… - Advanced …, 2022 - Wiley Online Library
Tumor immunotherapy is only effective in a fraction of patients due to a low response rate
and severe side effects, and these challenges of immunotherapy in clinics can be addressed …

[HTML][HTML] Recent advances in nanomedicines for photodynamic therapy (PDT)-driven cancer immunotherapy

B Ji, M Wei, B Yang - Theranostics, 2022 - ncbi.nlm.nih.gov
Cancer immunotherapy has made tremendous clinical progress in advanced-stage
malignancies. However, patients with various tumors exhibit a low response rate to …

Self‐sacrificially degradable pseudo‐semiconducting polymer nanoparticles that integrate NIR‐II fluorescence bioimaging, photodynamic immunotherapy, and photo …

D Tang, Y Yu, J Zhang, X Dong, C Liu… - Advanced …, 2022 - Wiley Online Library
Semiconducting polymers (SP) hold great promise for cancer phototherapy due to their
excellent optical properties; however, their clinical application is still hampered by their poor …

[HTML][HTML] A tumor cell membrane-coated self-amplified nanosystem as a nanovaccine to boost the therapeutic effect of anti-PD-L1 antibody

Z Li, H Cai, Z Li, L Ren, X Ma, H Zhu, Q Gong… - Bioactive materials, 2023 - Elsevier
To improve the response rate of immune checkpoint inhibitors such as anti-PD-L1 antibody
in immunosuppressive cancers like triple-negative breast cancer (TNBC), induction of …

Emerging photodynamic nanotherapeutics for inducing immunogenic cell death and potentiating cancer immunotherapy

S Zhang, J Wang, Z Kong, X Sun, Z He, B Sun, C Luo… - Biomaterials, 2022 - Elsevier
Immunotherapy has emerged as a promising cancer treatment modality. Despite the rapid
progress in cancer immunotherapy, the therapeutic efficiency and clinical translation of …

Bioorthogonal-activated in situ vaccine mediated by a COF-based catalytic platform for potent cancer immunotherapy

M Sun, Z Liu, L Wu, J Yang, J Ren… - Journal of the American …, 2023 - ACS Publications
Personalized tumor vaccines have become a promising modality for cancer immunotherapy.
However, in situ personalized tumor vaccines generated from immunogenic cancer cell …

A Multifunctional Cascade Bioreactor Based on Hollow‐Structured Cu2MoS4 for Synergetic Cancer Chemo‐Dynamic Therapy/Starvation Therapy/Phototherapy …

M Chang, M Wang, M Wang, M Shu, B Ding… - Advanced …, 2019 - Wiley Online Library
The unique tumor microenvironment (TME) facilitates cancer proliferation and metastasis,
and it is hard to cure cancer completely via monotherapy. Herein, a multifunctional cascade …

Polymer‐based mRNA delivery strategies for advanced therapies

W Yang, L Mixich, E Boonstra… - Advanced Healthcare …, 2023 - Wiley Online Library
Messenger RNA (mRNA)‐based therapies offer great promise for the treatment of a variety
of diseases. In 2020, two FDA approvals of mRNA‐based vaccines have elevated mRNA …

Current perspectives and trend of nanomedicine in cancer: A review and bibliometric analysis

Z Pei, S Chen, L Ding, J Liu, X Cui, F Li, F Qiu - Journal of Controlled …, 2022 - Elsevier
The limitations of traditional cancer treatments are driving the creation and development of
new nanomedicines. At present, with the rapid increase of research on nanomedicine in the …

[HTML][HTML] Circular RNA cancer vaccines drive immunity in hard-to-treat malignancies

H Li, K Peng, K Yang, W Ma, S Qi, X Yu, J He, X Lin… - Theranostics, 2022 - ncbi.nlm.nih.gov
Abstract Rationale: Messenger RNA (mRNA) vaccine outperforms other kinds of cancer
immunotherapy due to its high response rates, easy preparation, and wide applicability …