ABSTRACT MDR1 gene encodes for P glycoprotein (P-gp), which plays an important role in
bioavailability and cell-toxicity limitation of a wide range of drugs and xenobiotics. Three …

Introduction: In the absence of an HIV vaccine or cure, antiretroviral (ARV)-based prevention
strategies are being investigated to reduce HIV incidence. These prevention strategies …

To compare the effects of aminosalicylic acid, glucocorticoids and immunosuppressants on
the expression levels of multidrug resistance genes in patients with ulcerative colitis (UC) …

Inflammatory bowel disease (IBD) is a chronic and heterogeneous disorder characterized by
remitting and relapsing periods of activity. Pharmacogenetics refers to the study of the effect …

Genetic factors play a significant role in determining inflammatory bowel disease (IBD)
susceptibility. Epidemiologic data support genetic contribution to the pathogenesis of IBD …

Inflammatory bowel diseases (Crohn's disease and ulcerative colitis) are chronic
immunologically mediated diseases of the gut. Advances in genetics have revolutionized …

The ABCC subfamily contains thirteen members. Nine of these transporters are called
multidrug resistance proteins (MRPs). The MRPs have been associated with developing …

Background/Aims: Increased oxidative stress and decreased immune cell apoptosis have
been reported to be important factors in the pathogenesis of Crohn's disease (CD). Our aim …

Inflammatory bowel diseases (IBDs; eg, Crohn's disease [CD] and ulcerative colitis [UC]) are
chronic immunologically mediated diseases characterized by frequent relapses, often …

Inflammatory bowel disease includes ulcerative colitis (UC) and Crohn's disease (CD) of
unknown etiology. The expression of ATP‐binding cassette (ABC) family proteins has been …