Antibiotic-resistant ESKAPE pathogens and COVID-19: the pandemic beyond the pandemic

A Catalano, D Iacopetta, J Ceramella, M Pellegrino… - Viruses, 2023 - mdpi.com
Antibacterial resistance is a renewed public health plague in modern times, and the COVID-
19 pandemic has rekindled this problem. Changes in antibiotic prescribing behavior …

Sulbactam/durlobactam: first approval

SJ Keam - Drugs, 2023 - Springer
Abstract Sulbactam/durlobactam (XACDURO®), is a co-packaged antibacterial product that
has been developed by Entasis Therapeutics Inc. for the treatment of infections caused by …

Synthesis and clinical application of new drugs approved by FDA in 2023

YT Wang, PC Yang, YF Zhang, JF Sun - European Journal of Medicinal …, 2024 - Elsevier
In 2023, the US Food and Drug Administration (FDA) granted approval to a total of 55 new
drugs, comprising 29 new chemical entities (NCEs) and 25 new biological entities (NBEs) …

A comprehensive review of small molecule drugs approved by the FDA in 2023: Advances and prospects

YR Bai, DJ Seng, Y Xu, YD Zhang, WJ Zhou… - European Journal of …, 2024 - Elsevier
In 2023, the US Food and Drug Administration has approved 55 novel medications,
consisting of 17 biologics license applications and 38 new molecular entities. Although the …

Therapies in preclinical and in early clinical development for the treatment of urinary tract infections: from pathogens to therapies

V Fuochi, S Furnari, L Trovato, M Calvo… - Expert Opinion on …, 2024 - Taylor & Francis
ABSTRACT Introduction Urinary tract infections (UTIs) are a prevalent health challenge
characterized by the invasion and multiplication of microorganisms in the urinary system …

[HTML][HTML] Molecular epidemiology, microbiological features and infection control strategies for carbapenem-resistant Acinetobacter baumannii in a German burn and …

M Vital, S Woltemate, D Schlüter… - Antimicrobial …, 2024 - aricjournal.biomedcentral.com
Carbapenem-resistant Acinetobacter baumannii (CRAB) frequently causes both healthcare-
associated infections and nosocomial outbreaks in burn medicine/plastic surgery and …

Descriptive analysis of targeted carbapenemase genes and antibiotic susceptibility profiles among carbapenem-resistant Acinetobacter baumannii tested in the …

S Sabour, K Bantle, A Bhatnagar, JY Huang… - Microbiology …, 2024 - Am Soc Microbiol
Acinetobacter baumannii is a Gram-negative bacillus that can cause severe and difficult-to-
treat healthcare-associated infections. A. baumannii can harbor mobile genetic elements …

[HTML][HTML] Synergistic Activity of Cefiderocol in Combination with Avibactam, Sulbactam or Tazobactam against Carbapenem-Resistant Gram-Negative Bacteria

RE Lewis, M Palombo, E Diani, B Secci, D Gibellini… - Cells, 2024 - mdpi.com
We investigated the activity of cefiderocol/β-lactamase inhibitor combinations against clinical
strains with different susceptibility profiles to cefiderocol to explore the potentiality of …

Beyond resistance: assessing sulbactam-durlobactam's role in today's clinical landscape

AZ Al Meslamani - Expert Review of Anti-infective Therapy, 2024 - Taylor & Francis
Infectious diseases represent an ever-growing challenge, and antimicrobial resistance
(AMR) poses a significant threat to global health (1–3). Carbapenem-resistant Acinetobacter …

[HTML][HTML] Challenges and Emerging Molecular Approaches in Combating Antimicrobial Resistance

GPL Ynion, CJ Rosal, A Zulueta… - … of Bacteriology and …, 2024 - synapse.koreamed.org
Antimicrobial agents have been a crucial discovery in modern medicine and have
revolutionized the treatment of infectious diseases. However, the rampant overuse and …