Efficient exploration of protein conformational pathways using rrt* and mc

F Afrasiabi, N Haspel - Proceedings of the 11th ACM International …, 2020 - dl.acm.org
The conformational space of proteins is complex and high dimensional, which makes its
analysis a highly challenging task. Understanding the structure and dynamics of proteins is …

Integrating rigidity analysis into the exploration of protein conformational pathways using rrt* and mc

F Afrasiabi, R Dehghanpoor, N Haspel - Molecules, 2021 - mdpi.com
To understand how proteins function on a cellular level, it is of paramount importance to
understand their structures and dynamics, including the conformational changes they …

A novel data instance reduction technique using linear feature reduction

A Joshi, N Haspel - Journal of Artificial Intelligence and Systems, 2020 - iecscience.org
Representation of structurally significant data is indispensable to modern research. The
need for dimensionality reduction finds its foray in varied genres viz-a-viz, Structural …

Exploring the Conformational Space and Classification of Proteins Using Robotics-Based and Machine Learning Methods

F Afrasiabi - 2023 - search.proquest.com
Proteins are essential molecules in living organisms that perform a broad scope of
functionalities, such as catalyzing biochemical reactions, providing structural support, and …

Machine Learning Based Algorithms to Investigate Protein Structure

R Dehghanpoor - 2022 - search.proquest.com
The large scale of biological data becoming available in recent years requires advanced
computational methods capable of analyzing these complex, high-dimensional datasets to …