Practical review on the use of synchrotron based micro-and nano-X-ray fluorescence mapping and X-ray absorption spectroscopy to investigate the interactions …

HA Castillo-Michel, C Larue, AEP Del Real… - Plant Physiology and …, 2017 - Elsevier
The increased use of engineered nanomaterials (ENMs) in commercial products and the
continuous development of novel applications, is leading to increased intentional and …

Subcellular chemical imaging: new avenues in cell biology

J Decelle, G Veronesi, B Gallet, H Stryhanyuk… - Trends in cell …, 2020 - cell.com
To better understand the physiology and acclimation capability of the cell, one of the great
challenges of the future is to access the interior of a cell and unveil its chemical landscape …

Transmission-mode MALDI mass spectrometry imaging of single cells: optimizing sample preparation protocols

T Bien, S Bessler, K Dreisewerd… - Analytical chemistry, 2021 - ACS Publications
Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) makes
it possible to simultaneously visualize the spatial distribution of dozens to hundreds of …

X-ray ptychographic and fluorescence microscopy of frozen-hydrated cells using continuous scanning

J Deng, DJ Vine, S Chen, Q Jin, YSG Nashed… - Scientific Reports, 2017 - nature.com
X-ray microscopy can be used to image whole, unsectioned cells in their native hydrated
state. It complements the higher resolution of electron microscopy for submicrometer thick …

Preserving elemental content in adherent mammalian cells for analysis by synchrotron‐based x‐ray fluorescence microscopy

Q Jin, T Paunesku, B Lai, SC GLEBER… - Journal of …, 2017 - Wiley Online Library
Trace metals play important roles in biological function, and x‐ray fluorescence microscopy
(XFM) provides a way to quantitatively image their distribution within cells. The faithfulness …

SLC30A10 mutation involved in parkinsonism results in manganese accumulation within nanovesicles of the Golgi apparatus

A Carmona, CE Zogzas, S Roudeau… - ACS chemical …, 2018 - ACS Publications
Manganese (Mn) is an essential metal that can be neurotoxic when elevated exposition
occurs leading to parkinsonian-like syndromes. Mutations in the Slc30a10 gene have been …

Advances in element speciation analysis of biomedical samples using synchrotron-based techniques

F Porcaro, S Roudeau, A Carmona, R Ortega - TrAC Trends in Analytical …, 2018 - Elsevier
Synchrotron-radiation X-ray absorption spectroscopy (XAS) is a direct method for speciation
analysis with atomic resolution, providing information about the local chemical environment …

Chemical imaging analysis of the brain with X-ray methods

JF Collingwood, F Adams - Spectrochimica Acta Part B: Atomic …, 2017 - Elsevier
Cells employ various metal and metalloid ions to augment the structure and the function of
proteins and to assist with vital biological processes. In the brain they mediate biochemical …

Difficulties and artefacts in cryo-fixation of ovarian tissues for X-ray fluorescence analyses

A Gianoncelli, K Vogel-Mikuš, M Salomé… - Journal of Analytical …, 2023 - pubs.rsc.org
Even though measurements in cryogenic conditions are the preferred choice for single-cell
and plant analyses to reduce sample preparation artefacts, preserve the integrity of samples …

[HTML][HTML] Overview of chemical imaging methods to address biological questions

MML da Cunha, S Trepout, C Messaoudi, TD Wu… - Micron, 2016 - Elsevier
Chemical imaging offers extensive possibilities for better understanding of biological
systems by allowing the identification of chemical components at the tissue, cellular, and …