Neurobiological links between stress and anxiety

N Daviu, MR Bruchas, B Moghaddam, C Sandi… - Neurobiology of …, 2019 - Elsevier
Stress and anxiety have intertwined behavioral and neural underpinnings. These
commonalities are critical for understanding each state, as well as their mutual interactions …

Impact of anxiety on prefrontal cortex encoding of cognitive flexibility

J Park, B Moghaddam - Neuroscience, 2017 - Elsevier
Anxiety often is studied as a stand-alone construct in laboratory models. But in the context of
coping with real-life anxiety, its negative impacts extend beyond aversive feelings and …

Prefrontal excitatory/inhibitory balance in stress and emotional disorders: evidence for over-inhibition

CE Page, L Coutellier - Neuroscience & Biobehavioral Reviews, 2019 - Elsevier
Chronic stress-induced emotional disorders like anxiety and depression involve imbalances
between the excitatory glutamatergic system and the inhibitory GABAergic system in the …

[HTML][HTML] Animal models in psychiatric research: The RDoC system as a new framework for endophenotype-oriented translational neuroscience

E Anderzhanova, T Kirmeier, CT Wotjak - Neurobiology of stress, 2017 - Elsevier
Abstract The recently proposed Research Domain Criteria (RDoC) system defines
psychopathologies as phenomena of multilevel neurobiological existence and assigns them …

Reduced loss aversion in pathological gambling and alcohol dependence is associated with differential alterations in amygdala and prefrontal functioning

A Genauck, S Quester, T Wüstenberg, C Mörsen… - Scientific reports, 2017 - nature.com
Diagnostic criteria for pathological gambling and alcohol dependence (AD) include
repeated addictive behavior despite severe negative consequences. However, the concept …

Decreased autonomy in community-dwelling older adults

S Sánchez-García, C García-Peña… - … interventions in aging, 2019 - Taylor & Francis
Purpose The present study aims to explore characteristics associated with low perception of
autonomy among community-dwelling older adults. Patients and methods This original …

Medial prefrontal cortex encoding of stress and anxiety

DS Jacobs, B Moghaddam - International review of neurobiology, 2021 - Elsevier
The prefrontal cortex (PFC) is involved in adaptive control of behavior and optimizing action
selection. When an organism is experiencing an aversive event, such as a sustained state of …

Adaptive encoding of outcome prediction by prefrontal cortex ensembles supports behavioral flexibility

A Del Arco, J Park, J Wood, Y Kim… - Journal of …, 2017 - Soc Neuroscience
The prefrontal cortex (PFC) is thought to play a critical role in behavioral flexibility by
monitoring action–outcome contingencies. How PFC ensembles represent shifts in behavior …

Aberrant decision-making and drug addiction—how strong is the evidence?

H Ekhtiari, TA Victor, MP Paulus - Current opinion in behavioral sciences, 2017 - Elsevier
Highlights•Decision making dysfunction (DMD) is a core component of many aspects of drug
addiction.•DMD is a multifaceted construct that can be measured across multiple domains …

Mindfulness meditation improves visual short-term memory

MA Youngs, SE Lee, MO Mireku… - Psychological …, 2021 - journals.sagepub.com
Research into the effects of mindfulness meditation on behavioral outcomes has received
much interest in recent years, with benefits for both short-term memory and working memory …