The gut microbiome modulates neurochemical function and behavior and has been
implicated in numerous central nervous system (CNS) diseases, including developmental …

This paper is the forty-second consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

Clavulanic acid (CLAV) is a component of Augmentin® that preserves antibiotic efficacy by
inhibiting β-lactamase activity. It also enhances cellular glutamate uptake and is a potential …

The β-lactam antibiotic ceftriaxone (CTX) is a glutamate transporter subtype 1 (GLT-1)
enhancer that reduces cocaine reinforcing efficacy and relapse in rats, but pharmacokinetic …

Glutamate is the main excitatory neurotransmitter in the brain and is of critical importance for
the synaptic and circuit mechanisms that underlie opioid addiction. Opioid memories formed …

Drug addiction as a problem for the health of the individual and the society is the result of a
complex process in which there is an interaction between brain nuclei and neurotransmitters …

Background: Quetiapine is an atypical antipsychotic that antagonizes dopamine and
serotonin receptors. It has been suggested that quetiapine can be used to treat substance …

Mephedrone is a widely used drug of abuse, exerting its effects by interacting with
monoamine transporters. Although this mechanism has been widely studied heretofore, little …

Clavulanic acid (ClvA), a beta-lactamase inhibitor, is being explored for its significant
neuroprotective potential. The effects of ClvA were assessed both individually and in …

Clavulanic acid (CLAV) is a non-antibiotic β-lactam that has been used since the late 1970s
as a β-lactamase inhibitor in combination with amoxicillin, another ß-lactam with antibiotic …