Epithelial–mesenchymal transition in endometriosis—when does it happen?

L Konrad, R Dietze, MA Riaz, G Scheiner-Bobis… - Journal of Clinical …, 2020 - mdpi.com
Epithelial–mesenchymal transition (EMT) is an important process of cell remodeling
characterized by the gradual loss of the epithelial phenotype and progressive gain of a …

Noninvasive diagnosis of endometriosis: Review of current peripheral blood and endometrial biomarkers

I Flores, E Waelkens, T D'Hooghe - Best Practice & Research Clinical …, 2018 - Elsevier
A noninvasive biomarker-based test could help shorten the diagnostic delay for
endometriosis. The most investigated biomarker sources are peripheral blood and …

Current biomarkers for the detection of endometriosis

Z Tian, XH Chang, Y Zhao, HL Zhu - Chinese medical journal, 2020 - journals.lww.com
A clinically reliable non-invasive test for endometriosis is expected to reduce the diagnostic
delay. Although varieties of biomarkers have been investigated for decades, and cancer …

Is endometriosis due to evolutionary maladaptation?

S Mumusoglu, AJW Hsueh - Reproductive BioMedicine Online, 2024 - Elsevier
Similar to diabetes and unlike many pathogen-induced diseases, endometriosis is likely a
result of maladaptation to the evolutionary heritage of humans. The objective of this article is …

Non-invasive and mechanism-based molecular assessment of endometrial receptivity during the window of implantation: current concepts and future prospective …

B Sun, J Yeh - Frontiers in Reproductive Health, 2022 - frontiersin.org
Suboptimal endometrial receptivity and altered embryo-endometrial crosstalk account for
approximately two-thirds of human implantation failures. Current tests of the window of …

MicroRNA dysregulation and steroid hormone receptor expression in uterine tissues of rats with endometriosis during the implantation window

H Cai, XX Zhu, ZF Li, YP Zhu, JH Lang - Chinese Medical Journal, 2018 - mednexus.org
Background: Estrogen receptor (ER) and progesterone receptor (PR) are involved in
endometriosis, but the involvement of microRNAs (miRNAs) is unknown. The aim of the …

Label-free microfluidic chip for segregation and recovery of circulating leukemia cells: clinical applications in acute myeloid leukemia

D Ouyang, N Ye, Y Jiang, Y Wang, L Hu, S Chao… - Biomedical …, 2024 - Springer
We present a label-free microfluidic chip for the segregation of circulating leukemia cells
(CLCs) from blood samples, with a focus on its clinical applications in Acute Myeloid …

MiR-17-5p promoter methylation regulated by DNA methyltransferase 3 beta (DNMT3B) expedites endometriosis via the Krüppel-like factor 12 (KLF12)/Wnt/β-catenin …

X Yang, Y Tao, O Jin, J Lai, X Yang - Journal of Reproductive Immunology, 2023 - Elsevier
Endometriosis (EM) is a common chronic disease in women with a high incidence, and
aberrant DNA methylation and circulating endometrial cells (CECs) have been reported to …

Fibrinogen alpha chain is up-regulated and affects the pathogenesis of endometriosis

Y Chen, H Li, H Cheng, M Rui-Qiong, X Ye… - Reproductive …, 2019 - Elsevier
Research question In the group's previous study, fibrinogen alpha chain (FGA) was
identified as an up-regulated differential protein that was highly expressed in women with …

Circulating endometrial cells: a new source of information on endometriosis dynamics

E Pospisilova, I Kiss, H Souckova, P Tomes… - Journal of clinical …, 2019 - mdpi.com
The focus of the presented work was to isolate and characterize circulating endometrial cells
(CECs) enriched from peripheral blood (PB) of patients with diagnosed endometriosis. The …