Membrane lipids and cell signaling

H Sunshine, ML Iruela-Arispe - Current opinion in lipidology, 2017 - journals.lww.com
Membrane lipids and cell signaling : Current Opinion in Lipidology Membrane lipids and cell
signaling : Current Opinion in Lipidology Log in or Register Subscribe to journalSubscribe Get …

[HTML][HTML] Pathophysiological roles and applications of glycosphingolipids in the diagnosis and treatment of cancer diseases

X Jin, GY Yang - Progress in Lipid Research, 2023 - Elsevier
Glycosphingolipids (GSLs) are major amphiphilic glycolipids present on the surface of living
cell membranes. They have important biological functions, including maintaining plasma …

Ferulic acid protects hyperglycemia-induced kidney damage by regulating oxidative insult, inflammation and autophagy

S Chowdhury, S Ghosh, AK Das, PC Sil - Frontiers in Pharmacology, 2019 - frontiersin.org
Oxidative insult, inflammation, apoptosis and autophagy play a pivotal role in the etiology of
diabetic nephropathy, a global health concern. Ferulic acid, a phytochemical, is reported to …

Glycosyltransferases in cancer: prognostic biomarkers of survival in patient cohorts and impact on malignancy in experimental models

M Pucci, M Duca, N Malagolini, F Dall'Olio - Cancers, 2022 - mdpi.com
Simple Summary Cancer-associated glycosylation changes are widely used as biomarkers
and strongly impact malignancy. However, the clinical significance of the deranged …

The regulation of neutrophil migration in patients with sepsis: the complexity of the molecular mechanisms and their modulation in sepsis and the heterogeneity of …

Ø Bruserud, KA Mosevoll, Ø Bruserud, H Reikvam… - Cells, 2023 - mdpi.com
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host
response to infection. Common causes include gram-negative and gram-positive bacteria as …

B4GALNT1 induces angiogenesis, anchorage independence growth and motility, and promotes tumorigenesis in melanoma by induction of ganglioside GM2/GD2

H Yoshida, L Koodie, K Jacobsen, K Hanzawa… - Scientific reports, 2020 - nature.com
Abstract β-1, 4-N-Acetyl-Galactosaminyltransferase 1 (B4GALNT1) encodes the key enzyme
B4GALNT1 to generate gangliosides GM2/GD2. GM2/GD2 gangliosides are surface …

Lupeol alters viability of SK-RC-45 (Renal cell carcinoma cell line) by modulating its mitochondrial dynamics

K Sinha, S Chowdhury, S Banerjee, B Mandal… - Heliyon, 2019 - cell.com
Renal cell carcinoma (RCC) is the most common kidney cancer leading to 140,000 deaths
per year. Among all RCCs 80% evolve from the epithelial proximal tubular cells within the …

Glycosphingolipid dynamics in human embryonic stem cell and cancer: their characterization and biomedical implications

MY Ho, AL Yu, J Yu - Glycoconjugate Journal, 2017 - Springer
Glycosphingolipids (GSLs) are composed of complex glycans linked to sphingosines and
various fatty acid chains. Antibodies against several GSLs designated as stage-specific …

Multi-dimensional role of gangliosides in modulating cancer hallmarks and their prospects in targeted cancer therapy

A Sarkar, S Banerjee, K Biswas - Frontiers in Pharmacology, 2023 - frontiersin.org
Gangliosides are glycosphingolipids with prevalence in nervous tissue and their
involvement in certain neuronal diseases have been widely known. Interestingly, many …

[HTML][HTML] Eriodictyol mediated selective targeting of the TNFR1/FADD/TRADD axis in cancer cells induce apoptosis and inhibit tumor progression and metastasis

S Debnath, A Sarkar, DD Mukherjee, S Ray… - Translational …, 2022 - Elsevier
While the anti-inflammatory activities of Eriodictyol, a plant-derived flavonoid is well-known,
reports on its anti-cancer efficacy and selective cytotoxicity in cancer cells are still emerging …