Purpose Red wine polyphenols (RWP) are plant-based molecules that have been
extensively studied in relation to their protective effects on vascular health in both animals …

Significance: The vasculature responds to the respiratory needs of tissue by modulating
luminal diameter through smooth muscle constriction or relaxation. Coronary perfusion …

Aims Hypertension is one of the major causes of cardiac damage. In this study, the effects of
resveratrol supplementation and regular exercise on hypertension-induced cellular stress …

Ischemia-reperfusion (I/R) events are involved in the development of various ocular
pathologies, eg, retinal artery or vein occlusion. We tested the hypothesis that resveratrol is …

Olive leaves are rich in bioactive substances which exert anti-inflammatory, antioxidant,
insulin-sensitizing and antihypertensive effects. The aim of this study was to analyze the …

The microbial-mammalian metabolic axis has become recognized as an important
component governing the overall homeostatic balance of the mammalian host. Disruption of …

Vascular endothelial function declines with age on average, but there is high variability in
the magnitude of this decline within populations. Measurements of frailty, known as frailty …

Abstract Background Type II Diabetes mellitus (T2DM) patients are at the risk of developing
cerebrovascular diseases, often contributed by altered cerebral haemodynamics. We …

Adipose-derived stromal vascular fraction (SVF) has emerged as a potential regenerative
therapy, but few studies utilize SVF in a setting of advanced age. Additionally, the specific …

Due to the complexity of Alzheimer's disease, multiple cellular types need to be targeted
simultaneously in order for a given therapy to demonstrate any major effectiveness …