As an emerging cancer therapeutic target, non-apoptotic cell death such as ferroptosis,
necroptosis and pyroptosis, etc., has revealed significant potential in cancer treatment for …

Highlights•Discusses biological advantages of co-delivery of multiple agents in cancer
therapy.•Nanovehicles can be used for simultaneous delivery of drug–drug or drug–gene …

Amongst the various types of cancer, breast cancer is a highly heterogeneous disease and
known as the leading cause of death among women globally. The extensive interdisciplinary …

Paclitaxel, a compound naturally occurring in yew, is a commonly used drug for the
treatment of different types of cancer. Unfortunately, frequent cancer cell resistance …

Melatonin is a pleiotropic, indole secreted, and synthesized by the human pineal gland.
Melatonin has biological effects including anti-apoptosis, protecting mitochondria, anti …

Anomanolide C (AC), a natural withanolide isolated from Tubocapsicum anomalum, has
been reported to have exhibits remarkable anti-tumour activities in several types of human …

This study was aimed to design the first dual-target small-molecule inhibitor co-targeting
poly (ADP-ribose) polymerase-1 (PARP1) and bromodomain containing protein 4 (BRD4) …

Chemotherapy post cancer surgery has important clinical significance for reducing the
chance of recurrent-metastasis. However, postoperative chemotherapy efficacy is hampered …

Cisplatin is one of the most widely used anticancer agents for patients with tongue
squamous cell carcinoma (TSCC), but its efficacy is limited by chemoresistance …

Abstract The high probability (13%) of women developing breast cancer in their lifetimes in
America is exacerbated by the emergence of multidrug resistance after exposure to first-line …