About 60% of adults in the United States do not consume the estimated average
requirement for magnesium, but widespread pathological conditions attributed to …

Obesity and its associated metabolic dysregulation leading to metabolic syndrome is an
epidemic that poses a significant public health problem. More than one-third of the world …

AMPK, a metabolic sensor, protects against ischemic injury and cardiac hypertrophy
although its role in obesity is unclear. This study was designed to examine the impact of …

Background: Although nutritional, metabolic and cardiovascular abnormalities are
commonly seen in experimental studies of obesity, it is uncertain whether these effects result …

Risk for Atrial Fibrillation (AF), the most common human arrhythmia, has a major genetic
component. The T-box transcription factor TBX5 influences human AF risk, and adult-specific …

Previous studies show that exercise training and caloric restriction improve cardiac function
in obesity. However, the molecular mechanisms underlying this effect on cardiac function …

Obesity has been shown to impair myocardial performance. Nevertheless, the mechanisms
underlying the participation of calcium (Ca2+) handling on cardiac dysfunction in obesity …

Aims Leptin resistance has been associated with cardiac lipotoxicity; however, whether
leptin resistance is a risk factor associated with cardiac lipotoxicity at different time points in …

The system redox imbalance is one of the pathways related to obesity-related cardiac
dysfunction. Lycopene is considered one of the best antioxidants. The aim of this study was …

Obesity mechanisms that make atrial tissue vulnerable to arrhythmia are poorly understood.
Voltage-dependent potassium (IK, IKur, and IK1) and L-type calcium currents (ICa, L) are …