Precision medicine in human heart modeling: perspectives, challenges, and opportunities

M Peirlinck, FS Costabal, J Yao, JM Guccione… - … and modeling in …, 2021 - Springer
Precision medicine is a new frontier in healthcare that uses scientific methods to customize
medical treatment to the individual genes, anatomy, physiology, and lifestyle of each person …

State-of-the-art intra-procedural imaging for the mitral and tricuspid PASCAL Repair System

RT Hahn, SK Kodali - European Heart Journal-Cardiovascular …, 2022 - academic.oup.com
Advanced intra-procedural imaging techniques have been integral to technical and
procedural success transcatheter devices. A novel leaflet approximation therapy, the …

A comprehensive engineering analysis of left heart dynamics after MitraClip in a functional mitral regurgitation patient

A Caballero, W Mao, R McKay, RT Hahn… - Frontiers in …, 2020 - frontiersin.org
Percutaneous edge-to-edge mitral valve (MV) repair using MitraClip has been recently
established as a treatment option for patients with heart failure and functional mitral …

Mitral valve atlas for artificial intelligence predictions of MitraClip intervention outcomes

Y Dabiri, J Yao, VS Mahadevan, D Gruber… - Frontiers in …, 2021 - frontiersin.org
Severe mitral regurgitation (MR) is a cardiac disease that can lead to fatal consequences.
MitraClip (MC) intervention is a percutaneous procedure whereby the mitral valve (MV) …

Echocardiographic Outcomes With Transcatheter Edge-to-Edge Repair for Degenerative Mitral Regurgitation in Prohibitive Surgical Risk Patients

L Marcoff, K Koulogiannis, L Aldaia, A Mediratta… - Cardiovascular …, 2024 - jacc.org
Abstract Background The CLASP IID randomized trial (Edwards PASCAL TrAnScatheter
Valve RePair System Pivotal Clinical Trial) demonstrated the safety and effectiveness of the …

Management and outcome of failed percutaneous edge-to-edge mitral valve plasty: insight from an international registry

A Mangieri, F Melillo, C Montalto, P Denti, F Praz… - Cardiovascular …, 2022 - jacc.org
Objectives This study evaluated the incidence, management, and outcome of patients who
experienced MitraClip (Abbott Vascular) failure secondary to loss of leaflet insertion (LLI) …

A simulation study of the effects of number and location of MitraClips on mitral regurgitation

Y Dabiri, VS Mahadevan, JM Guccione, GS Kassab - JACC: Advances, 2022 - jacc.org
Background MitraClip (MC) is a device that is implanted on the mitral valve (MV)
percutaneously to treat severe mitral regurgitation (MR). It is common practice to place the …

In Silico Analysis of the MitraClip in a Realistic Human Left Heart Model

S Pasta - Prosthesis, 2023 - mdpi.com
Mitral valve regurgitation is a common heart valve disorder associated with significant
morbidity and mortality. Transcatheter mitral valve repair using the MitraClip device has …

A finite element model of the cardiac ventricles with coupled circulation: Biventricular mesh generation with hexahedral elements, airbags and a functional mockup …

Y Zhang, J Adams, VY Wang, L Horwitz… - Computers in Biology …, 2021 - Elsevier
Introduction Finite element (FE) mechanics models of the heart are becoming more
sophisticated. However, there is lack of consensus about optimal element type and coupling …

Tricuspid valve edge-to-edge repair simulations are highly sensitive to annular boundary conditions

CE Haese, V Dubey, M Mathur, AM Pouch… - Journal of the …, 2025 - Elsevier
Transcatheter edge-to-edge repair (TEER) simulations may provide insight into this novel
therapeutic technology and help optimize its use. However, because of the relatively short …