[HTML][HTML] Pharmaceutical strategies to extend pulmonary exposure of inhaled medicines

Y Guo, H Bera, C Shi, L Zhang, D Cun… - Acta Pharmaceutica Sinica …, 2021 - Elsevier
Pulmonary administration route has been extensively exploited for the treatment of local
lung diseases such as asthma, chronic obstructive pulmonary diseases and respiratory …

PLGA-based micro/nanoparticles: an overview of their applications in respiratory diseases

X Guo, X Zuo, Z Zhou, Y Gu, H Zheng, X Wang… - International Journal of …, 2023 - mdpi.com
Respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD),
are critical areas of medical research, as millions of people are affected worldwide. In fact …

Thermo-sensitive composite microspheres incorporating cellulose nanocrystals for regulated drug release kinetics

M Yang, SYH Abdalkarim, HY Yu, RAM Asad, D Ge… - Carbohydrate …, 2023 - Elsevier
Thermo-sensitive composite microspheres (TPCP) were developed to achieve the on-
demand release of drugs. The TPCP microspheres were synthesized using Oil-in-Water …

Microspheres for targeted drug delivery-A review on recent applications

AN Yawalkar, MA Pawar, PR Vavia - Journal of Drug Delivery Science and …, 2022 - Elsevier
Microspheres are one of the most explored drug carriers for site-specific delivery of cargoes
in a controlled and sustained manner. They are biocompatible, biodegradable, and are …

Recent advances in nanomaterials for asthma treatment

X Zuo, X Guo, Y Gu, H Zheng, Z Zhou, X Wang… - International Journal of …, 2022 - mdpi.com
Asthma is a chronic airway inflammatory disease with complex mechanisms, and these
patients often encounter difficulties in their treatment course due to the heterogeneity of the …

Lung targeted lipopolymeric microspheres of dexamethasone for the treatment of ARDS

S Kotta, HM Aldawsari, SM Badr-Eldin, LS Binmahfouz… - Pharmaceutics, 2021 - mdpi.com
Acute respiratory distress syndrome (ARDS), a catastrophic illness of multifactorial etiology,
involves a rapid upsurge in inflammatory cytokines that leads to hypoxemic respiratory …

Tackling the cytokine storm using advanced drug delivery in allergic airway disease

VK Patel, S Vishwas, R Kumar, G De Rubis… - Journal of Drug Delivery …, 2023 - Elsevier
Asthma is one of the leading causes of mortality worldwide presenting a huge socio-
economic burden with rising morbidity and mortality rates. It is a chronic inflammatory airway …

Delivery of Wnt inhibitor WIF1 via engineered polymeric microspheres promotes nerve regeneration after sciatic nerve crush

N Zhang, J Lin, JS Chin, C Wiraja… - Journal of Tissue …, 2022 - journals.sagepub.com
Injuries within the peripheral nervous system (PNS) lead to sensory and motor deficits, as
well as neuropathic pain, which strongly impair the life quality of patients. Although most …

Poloxamer 188 stabilized poly (ε-caprolactone) microspheres of voriconazole for targeting pulmonary aspergillosis

A Singh, A Mourya, H Singh, G Bajad, B Bojja… - Therapeutic …, 2024 - Taylor & Francis
Aim Voriconazole (VRZ) is highly effective in treating invasive pulmonary aspergillosis (IPA),
in addition to hepatotoxicity. Therefore, the current study focuses on the development and …

Targeted lung therapy with rosmarinic acid encapsulated in PLGA microspheres for radiation-induced pulmonary fibrosis

Y Chen, Y Li, Y He, L Shen, S Fu, L Qiao, Y Ran… - Journal of Drug Delivery …, 2024 - Elsevier
Radiation-induced pulmonary fibrosis (RIPF) is a frequent complication among individuals
affected by nuclear accidents and patients undergoing chest radiation therapy for tumors …