Lipid encapsulated messenger RNA (LNP mRNA) has garnered a significant amount of
interest from the pharmaceutical industry and general public alike. This attention has been …

Ribonucleases are ubiquitous in distribution. Ribonucleases that hydrolyse RNA to 3′
mononucleotides via 2′, 3′ cyclic nucleotides are classified into three groups, RNase A …

US7820378B2 - Fragmentation-based methods and systems for sequence variation detection
and discovery - Google Patents US7820378B2 - Fragmentation-based methods and systems …

It is surprising that only relatively recently has attention been directed to the characterization
of the properties of acid ribonucleases (RNases), leading to some understanding of their …

Characterization of mRNA sequences is a critical aspect of mRNA drug development and
regulatory filing. Herein, we developed a novel bottom-up oligonucleotide sequence …

Liquid chromatography tandem mass spectrometry (LC-MS/MS) has proven to be a powerful
analytical tool for the characterization of modified ribonucleic acids (RNAs). The typical …

A novel antifungal protein with its N-terminal sequence bearing similarity to the C-terminal
sequences of peroxidases was isolated from French bean legumes. The protein, which …

Oligonucleotides represent one of the most significant pharmaceutical breakthroughs in
recent years, showing great promise as diagnostic and therapeutic agents for malignant …

A recombinant ribonuclease, cusativin, was characterized for its cytidine-specific cleavage
ability of RNA to map chemical modifications. Following purification of native cusativin …

We characterised a cDNA encoding an S-like RNase (RNase NE) from the styles of the self-
incompatible plant, Nicotiana alata. RNase NE is 86% identical to an extracellular RNase …