The multifaceted contributions of mitochondria to cellular metabolism

JB Spinelli, MC Haigis - Nature cell biology, 2018 - nature.com
Although classically appreciated for their role as the powerhouse of the cell, the metabolic
functions of mitochondria reach far beyond bioenergetics. In this Review, we discuss how …

Proline mechanisms of stress survival

X Liang, L Zhang, SK Natarajan… - Antioxidants & redox …, 2013 - liebertpub.com
Significance: The imino acid proline is utilized by different organisms to offset cellular
imbalances caused by environmental stress. The wide use in nature of proline as a stress …

Proline and hydroxyproline metabolism: implications for animal and human nutrition

G Wu, FW Bazer, RC Burghardt, GA Johnson, SW Kim… - Amino acids, 2011 - Springer
Proline plays important roles in protein synthesis and structure, metabolism (particularly the
synthesis of arginine, polyamines, and glutamate via pyrroline-5-carboxylate), and nutrition …

Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals

I Kühl, M Miranda, I Atanassov, I Kuznetsova, Y Hinze… - elife, 2017 - elifesciences.org
Dysfunction of the oxidative phosphorylation (OXPHOS) system is a major cause of human
disease and the cellular consequences are highly complex. Here, we present comparative …

Proline Analogues

V Kubyshkin, M Rubini - Chemical Reviews, 2024 - ACS Publications
Within the canonical repertoire of the amino acid involved in protein biogenesis, proline
plays a unique role as an amino acid presenting a modified backbone rather than a side …

Exogenous vanillic acid enhances salt tolerance of tomato: Insight into plant antioxidant defense and glyoxalase systems

K Parvin, K Nahar, M Hasanuzzaman… - Plant Physiology and …, 2020 - Elsevier
We investigated vanillic acid-induced salt tolerance in tomato by exploring the plant defense
systems. Ten-d-old tomato (Solanum lycopersicum L. cv. Pusa Ruby) seedlings were treated …

Synthetic fusion protein design and applications

K Yu, C Liu, BG Kim, DY Lee - Biotechnology advances, 2015 - Elsevier
Synthetic fusion proteins can be designed to achieve improved properties or new
functionality by synergistically incorporating multiple proteins into one complex. The fusion …

[图书][B] Amino acid metabolism

DA Bender - 2012 - books.google.com
Amino Acid Metabolism, 3rd Edition covers all aspects of the biochemistry and nutritional
biochemistry of the amino acids. Starting with an overview of nitrogen fixation and the …

Evolution of proline biosynthesis: enzymology, bioinformatics, genetics, and transcriptional regulation

Y Fichman, SY Gerdes, H Kovács… - Biological …, 2015 - Wiley Online Library
Proline is not only an essential component of proteins but it also has important roles in
adaptation to osmotic and dehydration stresses, redox control, and apoptosis. Here, we …

Variation in relative water content, proline accumulation and stress gene expression in two cowpea landraces under drought

Z Zegaoui, S Planchais, C Cabassa, R Djebbar… - Journal of Plant …, 2017 - Elsevier
Many landraces of cowpea [Vigna unguiculata (L.) Walp.] are adapted to particular
geographical and climatic conditions. Here we describe two landraces grown respectively in …