Computational methods for chromosome-scale haplotype reconstruction

S Garg - Genome biology, 2021 - Springer
High-quality chromosome-scale haplotype sequences of diploid genomes, polyploid
genomes, and metagenomes provide important insights into genetic variation associated …

Hap10: reconstructing accurate and long polyploid haplotypes using linked reads

S Majidian, MH Kahaei, D De Ridder - BMC bioinformatics, 2020 - Springer
Background Haplotype information is essential for many genetic and genomic analyses,
including genotype-phenotype associations in human, animals and plants. Haplotype …

An extension of heuristic algorithm for reconstructing multiple haplotypes with minimum error correction

MM Hossain, ABM Abdullah… - … Emerging Technology in …, 2020 - ieeexplore.ieee.org
Human DNA consists of two copies of each chromosome. The haplotype assembly problem
focuses on the reconstruction of two sets of haplotypes (chromosomes) from aligned …