Purpose To review and synthesise prognostic indices that predict subsequent risk,
prescriptive indices that moderate treatment response, and mechanisms that underlie each …

Dopamine is an important neuromodulator that exerts widespread effects on the central
nervous system (CNS) function. Disruption in dopaminergic neurotransmission can have …

Long-term antidepressant treatment has increased and there is evidence of adverse effects;
however, little is known about patients' experiences and views of this form of treatment. This …

Heart rate variability (HRV) is a significant marker of health outcomes with decreased HRV
predicting increased disease risk. HRV is decreased in major depressive disorder (MDD) …

Background Long-term symptomatic status in persons with major depressive and bipolar
disorders treated clinically is not well established, although mood disorders are leading …

Whereas pharmacological interventions remain the primary treatment for bipolar disorders,
adjunctive psychosocial interventions have the potential to increase adherence to …

Mentalization has been proposed as a key concept in understanding therapeutic change in
patients with Borderline Personality Disorder (BPD). However, little is known about …

* Winner of an honorable mention from theSociety for Social Work and
ResearchforOutstanding Social Work Book AwardMad Science argues that the fundamental …

The aim of this article is to discuss the validity of relapse prevention trials and the issue of
withdrawal confounding in these trials. Recommendations for long-term antidepressant …

Background: Heart rate variability (HRV) mirrors cardiac autonomic modulation, an index of
well-being. Reduced HRV has been reported in depression, but few studies investigated …