[HTML][HTML] Extracellular matrix in high-grade serous ovarian cancer: Advances in understanding of carcinogenesis and cancer biology

Y Brown, S Hua, PS Tanwar - Matrix Biology, 2023 - Elsevier
High-grade serous ovarian cancer (HGSOC) is notoriously known as the “silent killer” of post-
menopausal women as it has an insidious progression and is the deadliest gynaecological …

A biological guide to glycosaminoglycans: current perspectives and pending questions

S Ricard‐Blum, RR Vivès, L Schaefer… - The FEBS …, 2024 - Wiley Online Library
Mammalian glycosaminoglycans (GAGs), except hyaluronan (HA), are sulfated
polysaccharides that are covalently attached to core proteins to form proteoglycans (PGs) …

Hyaluronan in the cancer cells microenvironment

E Karousou, A Parnigoni, P Moretto, A Passi, M Viola… - Cancers, 2023 - mdpi.com
Simple Summary The extracellular matrix has a complex structure, and the glycans within
are difficult to study, but are able to elicit multiple effects on resident and immune cells, with …

A highly selective red-emitting fluorescent probe and its micro-nano-assembly for imaging endogenous peroxynitrite (ONOO−) in living cells

J Zhang, L Liu, Y Wang, C Wang, Y Guo, Z Yuan… - Analytica Chimica …, 2023 - Elsevier
Endogenous peroxynitrite plays a very important role in the regulation of life activities.
However, validated tools for ONOO− tests are currently insufficient. We designed a …

[HTML][HTML] Small molecule inhibitors of mammalian glycosylation

K Almahayni, M Spiekermann, A Fiore, G Yu… - Matrix Biology Plus, 2022 - Elsevier
Glycans are one of the fundamental biopolymers encountered in living systems. Compared
to polynucleotide and polypeptide biosynthesis, polysaccharide biosynthesis is a uniquely …

Cancer immune exclusion: breaking the barricade for a successful immunotherapy

S Bruni, MF Mercogliano, FL Mauro… - Frontiers in …, 2023 - frontiersin.org
Immunotherapy has changed the course of cancer treatment. The initial steps were made
through tumor-specific antibodies that guided the setup of an antitumor immune response. A …

[HTML][HTML] Deciphering drug resistance: investigating the emerging role of hyaluronan metabolism and signaling and tumor extracellular matrix in cancer chemotherapy

DL Vitale, A Parnigoni, M Viola, E Karousou… - International Journal of …, 2024 - mdpi.com
Hyaluronan (HA) has gained significant attention in cancer research for its role in
modulating chemoresistance. This review aims to elucidate the mechanisms by which HA …

Hyaluronan network: A driving force in cancer progression

T Karalis, SS Skandalis - American Journal of Physiology …, 2022 - journals.physiology.org
Hyaluronan is one of the most abundant macromolecules of the extracellular matrix and
regulates several physiological cell and tissue properties. However, hyaluronan has been …

Potential of compounds originating from the nature to act in hepatocellular carcinoma therapy by targeting the tumor immunosuppressive microenvironment: a review

Y Li, H Li, Q He, X Yang - Molecules, 2022 - mdpi.com
Hepatocellular carcinoma (HCC), the most prevalent subtype of liver cancer, is the second
main reason for cancer-related deaths worldwide. In recent decades, sufficient evidence …

Biobased Composites from Eugenol-and Coumarin-Derived Methacrylic Latex and Hemp Nanocellulose: Cross-Linking via [2+ 2] Photocycloaddition and Barrier …

S Dalle Vacche, S Molina-Gutiérrez… - ACS Sustainable …, 2024 - ACS Publications
A novel-biobased latex was synthesized by redox-initiated emulsion copolymerization of
ethoxy dihydroeugenyl methacrylate with 5 wt% of a photosensitive methacrylate containing …