Abstract The interleukin-17 (IL-17) family consists of six family members (IL-17A–IL-17F) and
all the corresponding receptors have been identified recently. This family is mainly involved …

Chronic myeloid leukemia (CML) is a clonal myeloproliferative neoplasm driven by BCR-
ABL1 oncoprotein, which plays a pivotal role in CML pathology, diagnosis, and treatment as …

Interleukin-17 (IL-17) family cytokines are potent drivers of inflammatory responses.
Although IL-17 was originally identified as a cytokine that induces protective effects against …

Leukemia stem cells (LSCs) promote the disease and seem resistant to therapy and immune
control. Why LSCs are selectively resistant against elimination by CD8+ cytotoxic T cells …

Background and Objectives: Interleukin-17 (IL-17) is a cytokine family consisting of six
members and five specific receptors. IL-17A was the first member to be identified in 1993 …

Disease progression and relapse of chronic myeloid leukemia (CML) are caused by therapy
resistant leukemia stem cells (LSCs), and cure relies on their eradication. The …

Avian has a unique immune system that evolved in response to environmental pressures in
all aspects of innate and adaptive immune responses, including localized and circulating …

Abstract Purpose of Review Tyrosine kinase inhibitors (TKIs) are very successful for the
treatment of chronic myeloid leukaemia (CML) but are not curative in most patients due to …

Background: The clinical implementation of immune-checkpoint inhibitors (ICIs) targeting
CTLA4, PD-1, and PD-L1 has revolutionized the treatment of cancer. However, the majority …

Background Liver hepatocellular carcinoma (LIHC) is one of the malignant tumors with high
incidence as well as high death, which is ranked as the sixth most common tumor and the …