[HTML][HTML] Protective Effects of Exogenous Melatonin Administration on White Fat Metabolism Disruption Induced by Aging and a High-Fat Diet in Mice

D Lv, Y Ren, J Chen, Z Pang, Y Tang, L Zhang, L Yan… - Antioxidants, 2024 - mdpi.com
Obesity has emerged as a major risk factor for human health, exacerbated by aging and
changes in dietary habits. It represents a significant health challenge, particularly for older …

[HTML][HTML] 综合生物信息学方法识别精神分裂症状中关键线粒体自噬基因

廉坤, 李咏梅, 施诚龙, 陈怡兰, 张磊… - 昆明医科大学 …, 2025 - kyxuebao.kmmu.edu.cn
目的利用3D 脑类器官的单细胞及外周血转录组数据, 结合机器学习, 深入分析线粒体自噬基因在
精神分裂症(schizophrenia, SCZ) 中的作用. 方法结合两种机器学习算法, 通过外周血RNA …

Rab40 GTPases regulate AMBRA1-mediated transcription and cell migration

R Sampath, K Vaeth, V Mikalayeva, VA Skeberdis… - bioRxiv, 2024 - biorxiv.org
The Rab40 subfamily are unique small monomeric GTPases that form CRL5-based ubiquitin
E3 ligase complex and regulate ubiquitylation of specific target proteins. Recent studies …

Identify Key Mitochondrial Autophagy Genes in Schizophrenia through Integrated Bioinformatics Approaches

L Kun, LI Yongmei, SHI Chenglong, C Yilan… - 昆明医科大学 …, 2025 - kyxuebao.kmmu.edu.cn
Objective To utilize single-cell and peripheral blood transcriptomic data from 3D brain
organoids, combined with machine learning, to analyze the role of mitochondrial autophagy …