R-amino acid reductions, allow entry to other classes of compounds that are also useful as
the source of chiral centers, as with R-amino aldehydes, that, in turn, can be used in a …

The a-amino-carboxylic-acids are one of the five major classes of natural products and they
exhibit.-important and diverse biological functions.',* Historically, the aminoacids have been …

2-Oxazolines have permeated numerous sub-disciplines in synthetic organic chemistry in
the 100 years since their discovery. This versatile heterocycle has served as protecting …

Various chiral oxazolidinones (Evans' oxazolidinones) have been employed as effective
chiral auxiliaries in the asymmetric alkylation of different enolates. This strategy has been …

The oxazole is a five-membered aromatic heterocycle that contains both oxygen and
nitrogen. Oxazoles are numbered around the ring starting at the oxygen atom as shown …

A convergent asymmetric synthesis of the marinenatural product calyculin A has been
accomplished through the union of the two subunits comprising the C]-C2; and C26-C37 …

The regulation of cellular processes by the modulation of protein phosphorylation/
dephosphorylation is fundamental to a large number of, if not all, physiological functions …

γ-Amino acids have attracted considerable attention as biologically active compounds in the
central nervous system (CNS) of mammals. Over the last few years, significant interest in the …

With modern methods for asymmetric catalysis breaking ground, the use of chiral auxiliaries
seems to be old-fashioned and rather inefficient. However, for many transformations, chiral …

The total syntheses of aflastatin A and its C3–C48 degradation fragment (6a, R= H) have
been accomplished. The syntheses feature several complex diastereoselective fragment …