Relevance of IgE, allergy and eye rubbing in the pathogenesis and management of Keratoconus

P Ahuja, Z Dadachanji, R Shetty… - Indian journal of …, 2020 - journals.lww.com
Keratoconus (KC) is an ectatic disease of the cornea characterized by localized thinning and
protrusion causing irregular astigmatism, which can lead to significant visual impairment. KC …

How can we best diagnose severity levels of dry eye disease: current perspectives

T Chester, S Garg, J Johnston, B Ayers… - Clinical …, 2023 - Taylor & Francis
Dry eye disease (DED) is a common ocular condition, but the diagnosis relative to other
ocular conditions and the evaluation of severity of the condition has often been difficult. This …

Increased proinflammatory cytokines in tears correspond with conjunctival SARS-CoV-2 positivity in symptomatic COVID-19 patients

A Niedźwiedź, M Kawa, E Pius-Sadowska… - Scientific Reports, 2022 - nature.com
Tear fluid cytokine levels may serve as biomarkers of innate immune system response
against SARS-CoV-2 infection. Therefore, our aim was to analyze panel of selected …

Interleukin-4 stimulates lipogenesis in meibocytes by activating the STAT6/PPARγ signaling pathway

I Jun, BR Kim, SY Park, H Lee, J Kim, EK Kim, KY Seo - The Ocular Surface, 2020 - Elsevier
Purpose This study was performed to investigate the effects of interleukin (IL)-4 on
adipogenesis and the underlying molecular mechanisms in human meibomian gland …

Total IgE in tears accurately reflects the severity and predicts the prognosis of seasonal allergic conjunctivitis

J Bao, L Tian, Y Meng, B Wu, J Wang… - Clinical and …, 2022 - Wiley Online Library
Abstract Background Although immunoglobulin E (IgE) increases significantly in tears and
serum during seasonal allergic conjunctivitis (SAC), it is unclear whether tear total IgE can …

Sanitizer aerosol-driven ocular surface disease (SADOSD)—A COVID-19 repercussion?

R Shetty, C Jayadev, A Chabra… - Indian Journal of …, 2020 - journals.lww.com
Since the onset of the COVID-19 pandemic, there has been an advisory for regular and
thorough cleaning of hands besides other measures such as social distancing and self …

What's the situation with ocular inflammation? A cross-seasonal investigation of proteomic changes in ocular allergy sufferers' tears in Victoria, Australia

E Aydin, S Nie, S Azizoglu, L Chong… - Frontiers in …, 2024 - frontiersin.org
Background Ocular allergy (OA) is a localized subset of allergy characterized by ocular
surface itchiness, redness and inflammation. Inflammation and eye-rubbing, due to allergy …

Changes in anterior and posterior corneal elevation in patients with allergic conjunctivitis

Q Wang, F Yu, Z Feng, W Li, N Li, X Du, X Zhao… - Frontiers in …, 2021 - frontiersin.org
Purpose: To evaluate corneal elevation changes in patients with allergic conjunctivitis (AC)
and to analyze their correlations with ocular allergy signs and corneal biomechanical …

Survey of cytokines on ocular surfaces of atopic dogs by multiplex analysis using two sampling methods–a pilot study

C Pressanti, E Ravailhe, J Castellote‐Brun… - Veterinary …, 2021 - Wiley Online Library
Background Conjunctivitis in atopic dogs has already been described yet is rarely observed,
and likely underdiagnosed in practice. Objectives To assay various cytokines in tears and …

In vitro identification of drugs inducing systemic hypersensitivity reactions known in vivo to be associated with specific HLA genotypes

M Iulini, A Maddalon, V Galbiati, M Marinovich… - Toxicology in Vitro, 2020 - Elsevier
Hypersensitivity drug reactions (HDRs) are common among drugs, despite this, there are no
validated in vitro or in vivo methods for screening the sensitizing potential of drugs in the …