Uncovering ferroptosis in Parkinson's disease via bioinformatics and machine learning, and reversed deducing potential therapeutic natural products

P Wang, Q Chen, Z Tang, L Wang, B Gong, M Li… - Frontiers in …, 2023 - frontiersin.org
Objective: Ferroptosis, a novel form of cell death, is closely associated with excessive iron
accumulated within the substantia nigra in Parkinson's disease (PD). Despite extensive …

An Exome capture-based RNA-Sequencing assay for genome-wide identification and prioritization of clinically important fusions in Pediatric tumors

J Buckley, RJ Schmidt, D Ostrow, D Maglinte… - The Journal of Molecular …, 2024 - Elsevier
This study reports the development of an exome capture-based RNA-sequencing assay to
detect recurring and novel fusions in hematologic, solid, and central nervous system tumors …

[PDF][PDF] КОМПЛЕКСНЫЙ ПОДХОД ДЛЯ ИССЛЕДОВАНИЯ ОБРАЗЦОВ ПЛАЗМЫ КРОВИ: ПОВТОРЯЕМОСТЬ И ВОСПРОИЗВОДИМОСТЬ МЕТОДИКИ …

ВА Астафьева, ВВ Максютина… - КЛИНИЧЕСКАЯ …, 2024 - clinlabdia.ru
Совершенствование методик диагностики рака легкого (РЛ) направлено на увеличение
эффективности лекарственного и хирургического лечения за счет своевременного …

[PDF][PDF] Assessment and Application of Quality Control Strategies in Next-Generation Sequencing Data for Pediatric Cancer

M Rawat, AK Thongbam, R Das - researchgate.net
Next-generation sequencing (NGS) has transformed pediatric oncology by enabling precise
genetic profiling of various cancers, crucial for developing targeted diagnostics and …

[PDF][PDF] AN INTEGRATED APPROACH FOR STUDYING BLOOD PLASMA SAMPLES: REPEATABILITY AND REPRODUCIBILITY OF LUNG CANCER DIAGNOSIS …

IO Meshkov, AS Makarova, EA Snigir, PV Ershov… - iagnostika, 1955 - clinlabdia.ru
Improvement of methods for diagnostics of lung cancer (LC) is aimed at increasing the
effectiveness of drug and surgical treatment through timely detection of LC. Molecular …