l-Amino acid oxidase as biocatalyst: a dream too far?

L Pollegioni, P Motta, G Molla - Applied microbiology and biotechnology, 2013 - Springer
Abstract l-Amino acid oxidase (LAAO) is a flavoenzyme containing non-covalently bound
flavin adenine dinucleotide, which catalyzes the stereospecific oxidative deamination of l …

Synergistic strategies of predominant toxins in snake venoms

S Xiong, C Huang - Toxicology letters, 2018 - Elsevier
Synergism is a significant phenomenon present in snake venoms that may be an evolving
strategy to potentiate toxicities. Synergism exists between different toxins or toxin complexes …

[HTML][HTML] Effects of animal venoms and toxins on hallmarks of cancer

J Chaisakul, WC Hodgson, S Kuruppu… - Journal of …, 2016 - ncbi.nlm.nih.gov
Animal venoms are a cocktail of proteins and peptides, targeting vital physiological
processes. Venoms have evolved to assist in the capture and digestion of prey. Key venom …

Structure–function studies and mechanism of action of snake venom L-amino acid oxidases

A Ullah - Frontiers in pharmacology, 2020 - frontiersin.org
Snake venom L-amino acid oxidases (SV-LAAOs) are the least studied venom enzymes.
These enzymes catalyze the stereospecific oxidation of an L-amino acid to their …

The role of platelets in hemostasis and the effects of snake venom toxins on platelet function

MR de Queiroz, BB de Sousa, DF da Cunha Pereira… - Toxicon, 2017 - Elsevier
The human body has a set of physiological processes, known as hemostasis, which keeps
the blood fluid and free of clots in normal vessels; in the case of vascular injury, this process …

The enzymatic core of scorpion venoms

G Delgado-Prudencio, JI Cid-Uribe, JA Morales… - Toxins, 2022 - mdpi.com
Enzymes are an integral part of animal venoms. Unlike snakes, in which enzymes play a
primary role in envenomation, in scorpions, their function appears to be ancillary in most …

Snake venom components in medicine: From the symbolic rod of Asclepius to tangible medical research and application

MI Estevão-Costa, R Sanz-Soler… - The international journal …, 2018 - Elsevier
Both mythologically and logically, snakes have always fascinated man. Snakes have
attracted both awe and fear not only because of the elegant movement of their limbless …

The sequence and a three-dimensional structural analysis reveal substrate specificity among snake venom phosphodiesterases

A Ullah, K Ullah, H Ali, C Betzel, S ur Rehman - Toxins, 2019 - mdpi.com
(1) Background. Snake venom phosphodiesterases (SVPDEs) are among the least studied
venom enzymes. In envenomation, they display various pathological effects, including …

An update on potential molecular mechanisms underlying the actions of snake venom L-amino acid oxidases (LAAOs)

MV Paloschi, AS Pontes, AM Soares… - Current medicinal …, 2018 - ingentaconnect.com
Background: LAAOs (EC 1.4. 3.2) are found in concentrations that vary according to each
species of snakes; Viperidae, Crotalidae and Elapidae contain 1-9% of this enzyme in their …

Antimicrobial properties of L-amino acid oxidase: biochemical features and biomedical applications

K Kasai, M Nakano, M Ohishi, T Nakamura… - Applied Microbiology and …, 2021 - Springer
Mucus layer that covers the body surface of various animal functions as a defense barrier
against microbes, environmental xenobiotics, and predators. Previous studies have reported …