Protein phosphorylation is an important post‐transcriptional modification involving an
extremely wide range of intracellular signaling transduction pathways, making it an …

Idiopathic pulmonary fibrosis (IPF) is a long-lasting, continuously advancing, and irrevocable
interstitial lung disorder with an obscure origin and inadequately comprehended …

Idiopathic pulmonary fibrosis (IPF) is a fatal fibrotic lung disease associated with unremitting
fibroblast activation including fibroblast-to-myofibroblast transformation (FMT), migration …

Background Sodium glucose cotransporter 2 (SGLT2) inhibitors originally developed for the
treatment of type 2 diabetes are clinically very effective drugs halting chronic kidney disease …

Rho-associated coiled-coil-containing kinases (ROCKs), serine/threonine protein kinases,
were initially identified as downstream targets of the small GTP-binding protein Rho …

Objective Excessive extra-cellular-matrix production and uncontrolled proliferation of the
fibroblasts are characteristics of many fibrotic diseases, including idiopathic pulmonary …

Tissue remodeling/fibrosis is a main feature of idiopathic pulmonary fibrosis (IPF), which
results in the replacement of normal lung parenchyma with a collagen-rich extracellular …

Fibroblasts activation is a crucial process for development of fibrosis during idiopathic
pulmonary fibrosis pathogenesis, and transforming growth factor (TGF)-β1 plays a key …

Myocardial regeneration capacity declines during the first week after birth, and this decline is
linked to adaptation to oxidative metabolism. Utilizing this regenerative window, we …

Background Ensuring genetic integrity is essential during the cell cycle to avoid aneuploidy,
one of the underlying causes of malignancies. Aurora kinases are serine/threonine kinase …