Phenotype standardization for statin‐induced myotoxicity

A Alfirevic, D Neely, J Armitage… - Clinical …, 2014 - Wiley Online Library
Statins are widely used lipid‐lowering drugs that are effective in reducing cardiovascular
disease risk. Although they are generally well tolerated, they can cause muscle toxicity …

Statin‐associated autoimmune myopathy and anti‐HMGCR autoantibodies

P Mohassel, AL Mammen - Muscle & nerve, 2013 - Wiley Online Library
Statins are among the most commonly prescribed medications that significantly reduce
cardiovascular risk in selected individuals. However, these drugs can also be associated …

Atualização da diretriz brasileira de dislipidemias e prevenção da aterosclerose–2017

AA Faludi, MCO Izar, JFK Saraiva… - Arquivos brasileiros de …, 2017 - SciELO Brasil
Material de distribuição exclusiva à classe médica. Os Arquivos Brasileiros de Cardiologia
não se responsabilizam pelo acesso indevido a seu conteúdo e que contrarie a …

Drug allergies documented in electronic health records of a large healthcare system

L Zhou, N Dhopeshwarkar, KG Blumenthal, F Goss… - Allergy, 2016 - Wiley Online Library
Background The prevalence of drug allergies documented in electronic health records (EHR
s) of large patient populations is understudied. Objective We aimed to describe the …

Statin-associated myopathy and the quest for biomarkers: can we effectively predict statin-associated muscle symptoms?

DM Muntean, PD Thompson, AL Catapano… - Drug discovery today, 2017 - Elsevier
Highlights•Statin-associated muscle symptoms are the most common statin-related side
effects.•Lack of reliable diagnostic tests to assess SAMS is recognized as an unmet …

Effects of statins on skeletal muscle: a perspective for physical therapists

SL Di Stasi, TD MacLeod, JD Winters… - Physical …, 2010 - academic.oup.com
Hyperlipidemia, also known as high blood cholesterol, is a cardiovascular health risk that
affects more than one third of adults in the United States. Statins are commonly prescribed …

[PDF][PDF] Molecular mechanisms of statin intolerance

A Gluba-Brzozka, B Franczyk, P Toth, J Rysz… - Archives of Medical …, 2016 - termedia.pl
Statins reduce cardiovascular morbidity and mortality in primary and secondary prevention.
Despite their efficacy, many persons are unable to tolerate statins due to adverse events …

Muscle-and skeletal-related side-effects of statins: tip of the iceberg?

J Auer, H Sinzinger, B Franklin… - European Journal of …, 2016 - academic.oup.com
The clinical spectrum of muscle-and skeletal-related side-effects of statins includes varied
myalgias and weakness, an asymptomatic increase in the concentration of creatine kinase …

Low-dose aspirin use and recurrent gout attacks

Y Zhang, T Neogi, C Chen, C Chaisson… - Annals of the …, 2014 - ard.bmj.com
Objective To examine the association between cardioprotective use of low-dose aspirin and
the risk of recurrent gout attacks among gout patients. Methods We conducted an online …

Treating statin-intolerant patients

M Arca, G Pigna - … , metabolic syndrome and obesity: targets and …, 2011 - Taylor & Francis
Statins are effective in reducing cardiovascular events and are safe for almost all patients.
Nevertheless, intolerance to statins is frequently faced in clinical practice. This is mostly due …