[HTML][HTML] An update on β-sitosterol: A potential herbal nutraceutical for diabetic management

S Babu, S Jayaraman - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Phytosterols are bioactive compounds that are naturally present in plant cell membranes
with chemical structure similar to the mammalian cell-derived cholesterol. They are highly …

Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system

B Sarkadi, L Homolya, G Szakács… - Physiological …, 2006 - journals.physiology.org
In this review we give an overview of the physiological functions of a group of ATP binding
cassette (ABC) transporter proteins, which were discovered, and still referred to, as …

Effects of plant sterols and stanols on intestinal cholesterol metabolism: suggested mechanisms from past to present

ED Smet, RP Mensink, J Plat - Molecular nutrition & food …, 2012 - Wiley Online Library
Plant sterols and stanols are natural food ingredients found in plants. It was already shown
in 1950 that they lower serum low‐density lipoprotein cholesterol (LDL‐C) concentrations …

Critical analysis on characterization, systemic effect, and therapeutic potential of beta-sitosterol: a plant-derived orphan phytosterol

MS Bin Sayeed, SMR Karim, T Sharmin, MM Morshed - Medicines, 2016 - mdpi.com
Beta-sitosterol (BS) is a phytosterol, widely distributed throughout the plant kingdom and
known to be involved in the stabilization of cell membranes. To compile the sources …

Cholesterol and plant sterol absorption: recent insights

K Von Bergmann, T Sudhop, D Lütjohann - The American journal of …, 2005 - Elsevier
The recent discovery of transporters in the intestinal mucosa and the canalicular membrane
has given new insights into the regulation of intestinal absorption as well as the biliary …

Polymorphisms in the ABCG5 and ABCG8 genes associate with cholesterol absorption and insulin sensitivity

H Gylling, M Hallikainen, J Pihlajamäki, J Ågren… - Journal of lipid …, 2004 - ASBMB
The roles of polymorphisms of the sitosterolemia genes ABCG5 and ABCG8 in the
regulation of cholesterol metabolism and insulin sensitivity were studied in mildly …

A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol

EL Klett, K Lu, A Kosters, E Vink, MH Lee, M Altenburg… - BMC medicine, 2004 - Springer
Background Mutations in either of two genes comprising the STSL locus, ATP-binding
cassette (ABC)-transporters ABCG5 (encoding sterolin-1) and ABCG8 (encoding sterolin-2) …

[HTML][HTML] The ABCG5 polymorphism contributes to individual responses to dietary cholesterol and carotenoids in eggs

KL Herron, MM McGrane, D Waters, IE Lofgren… - The Journal of …, 2006 - Elsevier
The ATP binding cassette G5 (ABCG5) polymorphisms have been postulated to play a role
in the response to dietary cholesterol. The objective of this study was to examine the …

Cholesterol absorption from the intestine is a major determinant of reverse cholesterol transport from peripheral tissue macrophages

E Sehayek, SL Hazen - Arteriosclerosis, thrombosis, and vascular …, 2008 - Am Heart Assoc
Objective—We examined the effect of ezetimibe, a cholesterol absorption (CA) inhibitor, and
genetic determinants of CA on reverse cholesterol transport (RCT) from subcutaneously …

Plant sterols and stanols: their role in health and disease

SB Patel - Journal of Clinical Lipidology, 2008 - Elsevier
Mammalian physiological processes, and likely any organism with a biliary tree, can
distinguish between dietary cholesterol and noncholesterols, retaining very little of the …