In the last two decades, numerous in vitro studies demonstrated that insulin receptors and
theirs downstream pathways are widely distributed throughout the brain. This evidence has …

Metabolic syndrome (MS) is the term for a combination of hypertension, dyslipidemia, insulin
resistance, and central obesity as factors leading to cardiovascular and metabolic disease …

Abstract Introduction In Alzheimer's disease clinical research, glial fibrillary acidic protein
(GFAP) released/leaked into the cerebrospinal fluid and blood is widely measured and …

Ethnopharmacological relevance Bacopa floribunda (BF), a locally available plant has been
employed traditionally as memory enhancer in Southwestern, Nigeria. It has been utilized in …

The cognitive functions of people over 60 years of age have been diminished, due to the
structural and functional changes that the brain has during aging. The most evident changes …

Hippocampal neuronal death plays a causal role in the cognitive impairment of temporal
lobe epilepsy (TLE). Ferroptosis, a novel form of regulated cell death, is strongly linked to …

Metabolic syndrome (MS) results from excessive consumption of high‐calorie foods and
sedentary lifestyles. Clinically, insulin resistance, abdominal obesity, hyperglycemia …

Cadmium (Cd) is a heavy metal classified as a carcinogen whose exposure could affect the
function of the central nervous system. Studies suggest that Cd modifies neuronal …

Diabetes mellitus is a pandemic expected to spread from 422 million patients in 2014 to 592
million patients in 2035. Type 1 diabetes mellitus (T1D) is characterized by both …

The main characteristic of brain aging is an exacerbated inflammatory and oxidative
response that affects dendritic morphology and the function of the neurons of the prefrontal …