Psychedelics in psychiatry: neuroplastic, immunomodulatory, and neurotransmitter mechanisms

A Inserra, D De Gregorio, G Gobbi, M Nader - Pharmacological Reviews, 2021 - Elsevier
Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …

Biomarkers in psychiatry: concept, definition, types and relevance to the clinical reality

MS García-Gutiérrez, F Navarrete, F Sala… - Frontiers in …, 2020 - frontiersin.org
During the last years, an extraordinary effort has been made to identify biomarkers as
potential tools for improving prevention, diagnosis, drug response and drug development in …

[图书][B] Multisystemic resilience: Adaptation and transformation in contexts of change

M Ungar - 2021 - books.google.com
" Across diverse disciplines, the term resilience is appearing more and more often. However,
while each discipline has developed theory and models to explain the resilience of the …

Epigenetic mechanisms in schizophrenia and other psychotic disorders: a systematic review of empirical human findings

L Smigielski, V Jagannath, W Rössler, S Walitza… - Molecular …, 2020 - nature.com
Schizophrenia and other psychotic disorders are highly debilitating psychiatric conditions
that lack a clear etiology and exhibit polygenic inheritance underlain by pleiotropic genes …

DNA methylation and schizophrenia: current literature and future perspective

T Magwai, KB Shangase, FO Oginga, B Chiliza… - Cells, 2021 - mdpi.com
Schizophrenia is a neuropsychiatric disorder characterized by dissociation of thoughts, idea,
identity, and emotions. It has no central pathophysiological mechanism and precise …

Cross-tissue correlations of genome-wide DNA methylation in Japanese live human brain and blood, saliva, and buccal epithelial tissues

S Nishitani, M Isozaki, A Yao, Y Higashino… - Translational …, 2023 - nature.com
Neuroepigenetics considers genetic sequences and the interplay with environmental
influences to elucidate vulnerability risk for various neurological and psychiatric disorders …

Epigenetics in eating disorders: a systematic review

C Hübel, SJ Marzi, G Breen, CM Bulik - Molecular psychiatry, 2019 - nature.com
Eating disorders are complex heritable conditions influenced by both genetic and
environmental factors. Given the progress of genomic discovery in anorexia nervosa, with …

[HTML][HTML] Epigenetic effects of cannabis: A systematic scoping review of behavioral and emotional symptoms associated with cannabis use and exocannabinoid …

AS Machado, M Bragança, M Vieira-Coelho - Drug and alcohol …, 2024 - Elsevier
Background Recent research suggests that epigenetic modifications may mediate the
behavioral effects of cannabis, influencing exocannabinnoids' long term effects in cognitive …

The clinical significance of the glucocorticoid receptors: Genetics and epigenetics

R Motavalli, T Majidi, T Pourlak, S Abediazar… - The Journal of Steroid …, 2021 - Elsevier
The impacts of glucocorticoids (GCs) are mainly mediated by a nuclear receptor (GR)
existing in almost every tissue. The GR regulates a wide range of physiological functions …

Natural compound targeting BDNF V66M variant: insights from in silico docking and molecular analysis

A Sakhawat, MU Khan, R Rehman, S Khan, MA Shan… - Amb Express, 2023 - Springer
Abstract Brain-Derived Neurotrophic Factor (BDNF) is a neurotrophin gene family gene that
encodes proteins vital for the growth, maintenance, and survival of neurons in the nervous …