A state-of-the-art review on the NRF2 in Hepatitis virus-associated liver cancer

L Kalantari, ZR Ghotbabadi, A Gholipour… - Cell Communication and …, 2023 - Springer
According to a paper released and submitted to WHO by IARC scientists, there would be
905,700 new cases of liver cancer diagnosed globally in 2020, with 830,200 deaths …

[HTML][HTML] The nuclear factor erythroid 2-related factor 2/p53 axis in breast cancer

L Xia, W Ma, A Afrashteh, MA Sajadi, H Fakheri… - Biochemia …, 2023 - hrcak.srce.hr
Sažetak One of the most important factors involved in the response to oxidative stress (OS)
is the nuclear factor erythroid 2-related factor 2 (Nrf2), which regulates the expression of …

The emerging roles of sphingosine 1-phosphate and SphK1 in cancer resistance: a promising therapeutic target

SS Alkafaas, MI Elsalahaty, DF Ismail… - Cancer Cell …, 2024 - Springer
Cancer chemoresistance is a problematic dilemma that significantly restrains numerous
cancer management protocols. It can promote cancer recurrence, spreading of cancer, and …

Distinct Nrf2 signaling thresholds mediate lung tumor initiation and progression

JM DeBlasi, A Falzone, S Caldwell, N Prieto-Farigua… - Cancer research, 2023 - AACR
Mutations in the KEAP1–NRF2 (Kelch-like ECH-associated protein 1–nuclear factor-
erythroid 2 p45-related factor 2) pathway occur in up to a third of non–small cell lung cancer …

[HTML][HTML] Unveiling the dynamic interplay between cancer stem cells and the tumor microenvironment in melanoma: implications for novel therapeutic strategies

P Limonta, R Chiaramonte, L Casati - Cancers, 2024 - mdpi.com
Simple Summary Resistance to standard therapies represents a major challenge in
melanoma treatment. This is mainly related to the high heterogeneity of this malignancy due …

Determining expression changes of ANO7 and SLC38A4 membrane transporters in colorectal cancer

EM Khosroshahi, M Maghsoudloo, H Fahimi… - Heliyon, 2024 - cell.com
Membrane transporters are proteins responsible for facilitating the movement of molecules
within biological membranes. They play a vital role in maintaining cellular homeostasis by …

Potential roles of the exosome/microRNA axis in Breast cancer

AS Mamalo, V Alivirdiloo, A Sadeghnejad… - … -Research and Practice, 2023 - Elsevier
Cancer is one of the most common diseases in the world, and various genetic and
environmental factors play a key role in its development. Breast cancer is one of the most …

Potential Role of Nrf2, HER2, and ALDH in Cancer Stem Cells: A Narrative Review

A Fakhrioliaei, S Tanhaei, SA Pakmehr… - The Journal of …, 2024 - Springer
Cancer is one of the main causes of death among humans, second only to cardiovascular
diseases. In recent years, numerous studies have been conducted on the pathophysiology …

Mitigation of gestational diabetes-induced endothelial dysfunction through FGF21-NRF2 pathway activation involving L-Cystine

C Sun, L Wang, H Huang, Z Zheng, X Xu… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Gestational diabetes mellitus (GDM) disrupts glucolipid metabolism, endangering maternal
and fetal health. Despite limited research on its pathogenesis and treatments, we conducted …

Investigating the Difference Between Electron and Photon Radiation in Radiotherapy

AA Koshki, G Tanzifi - Eurasian Journal of Chemical, Medicinal and …, 2023 - ejcmpr.com
Radiotherapy may help achieve different treatment goals. For example, it may increase the
effectiveness of surgery, help prevent cancer from spreading, or reduce symptoms of …