PURPOSE The terms undertreatment and overtreatment are often used to describe
inappropriate management of older adults with cancer. We conducted a comprehensive …

Significant progress has been made toward improving the care of older adults with cancer.
As described elsewhere in this Special Series, the evidence base in geriatric oncology has …

We should adopt a health ecosystems approach to mental healthcare and training,
encompassing nano to macrolevels of service in every region. Catchment mental health …

A lively topic of debate in decision theory over recent years concerns our understanding of
the different risk attitudes exhibited by decision makers. There is ample evidence that risk …

beta lactamase AmpC; colistin; extended spectrum beta lactamase; food additive; growth
promotor; mcr 1 protein; unclassified drug; antiinfective agent; agricultural worker; …

The COVID-19 pandemic represents the world's worst public health threat since the 1918 flu
pandemic. Infected persons face the prospect of serious pneumonia, progression to critical …

Building interpretable parameterizations of real-world decision-making on the basis of
demonstrated behavior--ie trajectories of observations and actions made by an expert …

Background Current methods for developing clinical practice guidelines have several
limitations: they are characterised by the “black box” operation—a process with defined …

The generation of neuropathic pain is a complex dynamic process. Factors involved include
one or more dysregulated sensory neural pathways; dysregulated activity of specific …

Background Contemporary delivery of health care is inappropriate in many ways, largely
due to suboptimal Q5 decision‐making. A typical approach to improve practitioners' decision …