Management of gastroesophageal reflux disease (GERD) commonly starts with an empiric
trial of proton pump inhibitor (PPI) therapy and complementary lifestyle measures, for …

Gastro-oesophageal reflux disease is one of the most common disorders of the
gastrointestinal tract. Over past decades, considerable shifts in thinking about the disease …

Electrical stimulation is a promising method to modulate gastrointestinal disorders. However,
conventional stimulators need invasive implantation and removal surgeries associated with …

A significant percentage of patients with gastroesophageal reflux disease (GERD) will not
respond to proton pump inhibitor (PPI) therapy. The causes of PPI-refractory GERD are …

Abstract Purpose of Review Despite the many areas of unmet needs in gastroesophageal
reflux disease (GERD), proton pump inhibitors (PPIs) remain the cornerstone of medical …

胃食管反流病患病率逐年升高, 临床表现复杂多样, 需要新型技术协助诊断, 这些新型诊断手段也
促进胃食管反流病发病机制的深入研究. 近年质子泵抑制剂及胃肠动力药长期使用的不良反应备 …

Background Lower esophageal sphincter (LES) electrical stimulation therapy (EST) has
been shown to improve outcome in gastroesophageal reflux disease (GERD) patients at 1 …

Background Electrical stimulation of the lower esophageal sphincter (LES) improves LES
pressure without interfering with LES relaxation. The aim of this open-label pilot trial was to …

Background and study aims: In patients with gastroesophageal reflux disease (GERD),
temporary electrical stimulation of the lower esophageal sphincter (LES) increases LES …

Background A previous single‐centre study showed that lower oesophageal sphincter
electrical stimulation therapy (LES‐EST) in gastro‐oesophageal reflux disease (GERD) …