NAFLD in children: new genes, new diagnostic modalities and new drugs

V Nobili, A Alisi, L Valenti, L Miele… - Nature reviews …, 2019 - nature.com
Nonalcoholic fatty liver disease (NAFLD) has rapidly become the most common form of
chronic liver disease in children and adolescents. Over the past 5 years, developments have …

[HTML][HTML] Pathogenesis of non-alcoholic fatty liver disease in children and adolescence: From “two hit theory” to “multiple hit model”

YL Fang, H Chen, CL Wang, L Liang - World journal of …, 2018 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) has become the dominant form of chronic liver
disease in children and adolescents with the increasing prevalence of obesity worldwide …

Prevalence of liver steatosis and fibrosis detected by transient elastography in adolescents in the 2017–2018 National Health and Nutrition Examination Survey

S Ciardullo, T Monti, G Perseghin - Clinical gastroenterology and …, 2021 - Elsevier
Background & Aims Metabolic-associated fatty liver disease (MAFLD) is common among
adolescents, but the prevalence of significant fibrosis in this age group is not known. We …

Childhood obesity, cardiovascular and liver health: a growing epidemic with age

MF Faienza, M Chiarito, E Molina-Molina… - World journal of …, 2020 - Springer
Background The frequency of childhood obesity has increased over the last 3 decades, and
the trend constitutes a worrisome epidemic worldwide. With the raising obesity risk, key …

Sulforaphane attenuates nonalcoholic fatty liver disease by inhibiting hepatic steatosis and apoptosis

J Li, S Xie, W Teng - Nutrients, 2021 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is characterized by lipotoxicity and ectopic lipid
deposition within hepatocytes. Sulforaphane (SFA), an active compound used for inhibiting …

Oxidized lipids: common immunogenic drivers of non-alcoholic fatty liver disease and atherosclerosis

C Hoebinger, D Rajcic, T Hendrikx - Frontiers in cardiovascular …, 2022 - frontiersin.org
The prevalence of non-alcoholic fatty liver disease (NAFLD), ranging from simple steatosis
to inflammatory steatohepatitis (NASH) and cirrhosis, continues to rise, making it one of the …

[PDF][PDF] Impact of the new definition of metabolic dysfunction–associated fatty liver disease on detection of significant liver fibrosis in US adolescents

S Ciardullo, M Carbone, P Invernizzi… - Hepatology …, 2022 - Wiley Online Library
Recently, an expert panel proposed diagnostic criteria for metabolic dysfunction–associated
fatty liver disease (MAFLD) in the pediatric population. The aim of this study was to evaluate …

Comparative efficacy of different treatment modalities in the management of pediatric non-alcoholic fatty liver disease: A systematic review and network meta-analysis

X Theodoridis, G Kalopitas, A Vadarlis… - Pharmacology & …, 2022 - Elsevier
The incidence of non-alcoholic fatty liver disease (NAFLD) in children is constantly rising.
Lifestyle modification is the cornerstone of the management of pediatric NAFLD. Even …

[HTML][HTML] Machine learning models for predicting non-alcoholic fatty liver disease in the general United States population: NHANES database

A Atsawarungruangkit, P Laoveeravat… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Machine learning models for predicting non-alcoholic fatty liver disease in the general United
States population: NHANES database - PMC Back to Top Skip to main content NIH NLM Logo …

High protein diet and metabolic plasticity in non-alcoholic fatty liver disease: myths and truths

F De Chiara, C Ureta Checcllo, J Ramon Azcon - Nutrients, 2019 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is characterized by lipid accumulation within the
liver affecting 1 in 4 people worldwide. As the new silent killer of the twenty-first century …