Bone loss in space travelers is a major challenge for long-duration space exploration. To
quantify microgravity-induced bone loss in humans, we performed a meta-analysis of …

Abstract Space medicine is fundamental to the human exploration of space. It supports
survival, function and performance in this challenging and potentially lethal environment. It is …

Abstract Background Context Prolonged microgravity exposure is associated with localized
low back pain and an elevated risk of post-flight disc herniation. Although the mechanisms …

Study Design. Prospective case series. Objective. Determine the extent of paraspinal muscle
cross-sectional area (CSA) and attenuation change after long-duration spaceflight and …

Background: Space Agencies are planning human missions beyond Low Earth Orbit.
Consideration of how physiological system adaptation with microgravity (μG) will be …

Ground‐based animal models have been used extensively to understand the effects of
microgravity on various physiological systems. Among them, hindlimb suspension (HLS) …

Background There is a need to ascertain the type and level of treatment burden experienced
by people with co-morbidities. This is important to identify the characteristics of participants …

Abstract Lower Body Negative Pressure (LBNP) redistributes blood from the upper body to
the lower body. LBNP may prove to be a countermeasure for the multifaceted physiological …

Background The constraints of the Orion Multi-Purpose Crew Vehicle present challenges to
the use of current exercise countermeasures necessary to prevent severe deconditioning of …

Long-duration spaceflight has been shown to negatively affect the lumbopelvic muscles of
crewmembers. Through analysis of computed tomography scans of crewmembers on 4-to 6 …