Review of lipoic acid: from a clinical therapeutic agent to various emerging biomaterials

S Lv, S He, X Ling, Y Wang, C Huang, J Long… - International Journal of …, 2022 - Elsevier
Lipoic acid (LA), an endogenous small molecule in organisms, has been extensively used
for the highly efficient clinical treatment of malignant diseases, which include diabetes …

Applications of sharpless asymmetric dihydroxylation in the total synthesis of natural products

MM Heravi, V Zadsirjan, M Esfandyari… - Tetrahedron: Asymmetry, 2017 - Elsevier
Sharpless asymmetric dihydroxylation involves the reaction of an alkene with osmium
tetroxide in the presence of a chiral quinine ligand to form an optically active vicinal diol …

Ligand-modulated nickel-catalyzed regioselective silylalkylation of alkenes

C Ding, Y Ren, Y Yu, G Yin - Nature Communications, 2023 - nature.com
Organosilicon compounds have shown tremendous potential in drug discovery and their
synthesis stimulates wide interest. Multicomponent cross-coupling of alkenes with silicon …

Transfer hydrogenation of cyclic carbonates and polycarbonate to methanol and diols by iron pincer catalysts

X Liu, JG de Vries, T Werner - Green Chemistry, 2019 - pubs.rsc.org
Herein, we report the first example on the use of an earth-abundant metal complex as the
catalyst for the transfer hydrogenation of cyclic carbonates to methanol and diols. The …

α-Lipoic acid chemistry: the past 70 years

JQ Wang, X Ling, HJ Wang, FE Chen - RSC advances, 2023 - pubs.rsc.org
α-Lipoic acid (ALA) is a naturally occurring sulfur-containing fatty acid with high antioxidant
activity. It is also used to treat diabetes, nerve pain, weight loss, heart disease, and primary …

Preparation of chitosan molecularly imprinted polymers and the recognition mechanism for adsorption of alpha-lipoic acid

L Xu, ZX Zhao, YA Huang, QJ Zhu - Molecules, 2020 - mdpi.com
Two effective molecularly imprinted polymers for the adsorption of alpha-lipoic acid (ALA)
were synthesized by the cross-linking of chitosan with epichlorohydrin (ECH) and …

Effects of Silver Carbonate and p-Nitrobenzoic Acid for Accelerating Palladium-Catalyzed Allylic C–H Acyloxylation

A Skhiri, H Nagae, H Tsurugi, M Seki… - Organic Letters, 2021 - ACS Publications
An allylic C–H acyloxylation of terminal alkenes with 4-nitrobenzoic acid was assisted by a
bidentate-sulfoxide-ligated palladium catalyst combined with 1, 4-benzoquinone and …

Small molecules for the improvement of mechanical properties and degradation of photopolymers

L Sinawehl - 2023 - repositum.tuwien.at
In case of critical bone loss due to accidents or diseases, the process of bone regeneration
cannot be fulfilled, and additional surgical intervention in the form of bone transplants is …

Rational Design and Experimental Research on the Self‐Assembled System of Thermosensitive Molecularly Imprinted Polymers Formed by α‐Lipoic Acid and N …

YQ Chen, BW Yang, YA Huang… - … Journal of Polymer …, 2021 - Wiley Online Library
In this paper, the main work was to study the theoretical self‐assembly process of
thermosensitive molecularly imprinted polymers (MIPs) for α‐lipoic acid and to investigate …

Late-Stage Diversification of Select Natural Products: New Chemical Entities with Improved Biological Activities

MJS Alqahtani - 2022 - search.proquest.com
Owing to their complexity, diverse structures and molecular targets, natural products have
contributed, and will continue to contribute, to the development and discovery of new drugs …