[HTML][HTML] Antibacterial coatings on orthopedic implants

X Chen, J Zhou, Y Qian, LZ Zhao - Materials Today Bio, 2023 - Elsevier
With the aging of population and the rapid improvement of public health and medical level in
recent years, people have had an increasing demand for orthopedic implants. However …

Implant materials and prosthetic joint infection: the battle with the biofilm

DJ Davidson, D Spratt, AD Liddle - EFORT open reviews, 2019 - eor.bioscientifica.com
Prosthetic joint infection (PJI) is associated with poor clinical outcomes and is expensive to
treat. Although uncommon overall (affecting between 0.5% and 2.2% of cases), PJI is one of …

Recent strategies to combat infections from biofilm-forming bacteria on orthopaedic implants

EC Rodríguez-Merchán, DJ Davidson… - International Journal of …, 2021 - mdpi.com
Biofilm-related implant infections (BRII) are a disastrous complication of both elective and
trauma orthopaedic surgery and occur when an implant becomes colonised by bacteria. The …

The serum level of C-reactive protein alone cannot be used for the diagnosis of prosthetic joint infections, especially in those caused by organisms of low virulence

D Akgün, M Müller, C Perka… - The bone & joint journal, 2018 - boneandjoint.org.uk
Aims The aim of this study was to determine the prevalence and characteristics of C-reactive
protein (CRP)-negative prosthetic joint infection (PJI) and evaluate the influence of the type …

Direct detection and identification of periprosthetic joint infection pathogens by metagenomic next-generation sequencing

L Hao, P Wen, W Song, B Zhang, Y Wu, Y Zhang… - Scientific Reports, 2023 - nature.com
This study assessed the application of metagenomic next-generation sequencing in
pathogen detection of periprosthetic joint infections. A total of 95 cases who previously had …

Outcome of hip and knee periprosthetic joint infections caused by pathogens resistant to biofilm-active antibiotics: results from a prospective cohort study

D Akgün, C Perka, A Trampuz, N Renz - Archives of orthopaedic and …, 2018 - Springer
Background Periprosthetic joint infections (PJI) caused by pathogens, for which no biofilm-
active antibiotics are available, are often referred to as difficult-to-treat (DTT). However, it is …

Periprosthetic bacterial biofilm and quorum sensing

JA Mooney, EM Pridgen, R Manasherob… - Journal of …, 2018 - Wiley Online Library
Periprosthetic joint infection (PJI) is a common complication after total joint arthroplasty
leading to severe morbidity and mortality. With an aging population and increasing …

A positive bacterial culture during re-implantation is associated with a poor outcome in two-stage exchange arthroplasty for deep infection

D Akgün, M Müller, C Perka… - The Bone & Joint …, 2017 - boneandjoint.org.uk
Aims The aim of this study was to identify the incidence of positive cultures during the
second stage of a two-stage revision arthroplasty and to analyse the association between …

The impact of methicillin resistance on clinical outcome among patients with Staphylococcus aureus osteomyelitis: a retrospective cohort study of 482 cases

H Wu, C Jia, X Wang, J Shen, J Tan, Z Wei, S Wang… - Scientific Reports, 2023 - nature.com
This study was designed to evaluate the impact of methicillin resistance on the outcomes
among patients with S. aureus osteomyelitis. We reviewed all extremity osteomyelitis …

High cure rate of periprosthetic hip joint infection with multidisciplinary team approach using standardized two-stage exchange

D Akgün, M Müller, C Perka, T Winkler - Journal of Orthopaedic Surgery …, 2019 - Springer
Background Two-stage exchange arthroplasty is still the preferred treatment choice for
chronic PJI. However, the results remain unpredictable. We analyzed the treatment success …