ABSTRACT Exosomes are small ($30–140 nm) lipid bilayer-enclosed particles of endosomal origin. They are a subset of extracellular vesicles (EVs) that are secreted by most …
H Shin, BH Choi, O Shim, J Kim, Y Park, SK Cho… - Nature …, 2023 - nature.com
Early cancer detection has significant clinical value, but there remains no single method that can comprehensively identify multiple types of early-stage cancer. Here, we report the …
Owing to the relationship between extracellular vesicles (EVs) and physiological and pathological conditions, the interest in EVs is exponentially growing. EVs hold high hopes …
R Kalluri - The Journal of clinical investigation, 2016 - Am Soc Clin Investig
Humans circulate quadrillions of exosomes at all times. Exosomes are a class of extracellular vesicles released by all cells, with a size range of 40–150 nm and a lipid …
CF Ruivo, B Adem, M Silva, SA Melo - Cancer research, 2017 - AACR
Exosomes are a subclass of extracellular vesicles involved in intercellular communication that are released by all cell types, including cancer cells. Cancer exosomes carry malignant …
SM Gysler, R Drapkin - The Journal of clinical investigation, 2021 - Am Soc Clin Investig
In recent decades, cancer research has expanded exponentially beyond the study of abnormally dividing cells to include complex and extensive heterotypic interactions between …
SW Ferguson, J Wang, CJ Lee, M Liu… - Scientific reports, 2018 - nature.com
Mesenchymal stem cell (MSC)-derived exosomes mediate tissue regeneration in a variety of diseases including ischemic heart injury, liver fibrosis, and cerebrovascular disease. Despite …
K Essandoh, L Yang, X Wang, W Huang, D Qin… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Sepsis is an infection-induced severe inflammatory disorder that leads to multiple organ failure. Amongst organs affected, myocardial depression is believed to be a major …
Mesenchymal stem cells (MSCs) have been shown to elicit cardio-protective effects in sepsis. However, the underlying mechanism remains obscure. While recent studies have …