Cardiovascular diseases (CVDs), such as ischaemic heart disease, cardiomyopathy,
atherosclerosis, hypertension, stroke and heart failure, are among the leading causes of …

A link between oxidative stress and hypertension has been firmly established in multiple
animal models of hypertension but remains elusive in humans. While initial studies focused …

The etiology of hypertension involves complex interactions among genetic, environmental,
and pathophysiologic factors that influence many regulatory systems. Hypertension is …

Vascular Nox (NADPH oxidase)-derived reactive oxygen species and endoplasmic
reticulum (ER) stress have been implicated in hypertension. However, relationships …

Under physiological conditions, reactive oxygen species (ROS) function as signaling
molecules that control cell function. However in pathological conditions, increased …

Dementia refers to a particular group of symptoms characterized by difficulties with memory,
language, problem-solving, and other thinking skills that affect a person's ability to perform …

The endoplasmic reticulum (ER) plays a vital function in maintaining cellular homeostasis.
Endoplasmic reticulum stress (ERS) can trigger various modes of cell death by activating the …

Metabolism of carbohydrates and lipids and protein degradation occurs in the liver and
contributes to the body's homeostasis by secreting a variety of mediators. Any imbalance in …

Stroke is one of the major causes of death and long-term disability, of which acute ischemic
stroke (AIS) is the most common type. Although circular RNA (circRNA) expression profiles …

Aging and major chronic diseases are risk factors for lower urinary tract symptoms (LUTS).
On the other hand, oxidative stress (OS) is one of the fundamental mechanisms of aging and …