The role of ribosomal DNA methylation in embryonic development, aging and diseases
The ribosomal DNA (rDNA) constitutes a remarkably conserved DNA sequence within
species, located in the area of the nucleolus, and responsible for coding three major types of …
species, located in the area of the nucleolus, and responsible for coding three major types of …
Ribosomal DNA copy number is associated with body mass in humans and other mammals
PP Law, LA Mikheeva, F Rodriguez-Algarra… - Nature …, 2024 - nature.com
Body mass results from a complex interplay between genetics and environment. Previous
studies of the genetic contribution to body mass have excluded repetitive regions due to the …
studies of the genetic contribution to body mass have excluded repetitive regions due to the …
The ribosome's comeback: new role in body weight regulation
L Srour, N El Hajj - Trends in Genetics, 2024 - cell.com
The recent discovery of an association between ribosomal DNA (rDNA) copy number and
body mass index (BMI) by Law et al. sheds light on a possible role of 45S rDNA in body …
body mass index (BMI) by Law et al. sheds light on a possible role of 45S rDNA in body …
Germline ecology: Managed herds, tolerated flocks, and pest control
D Haig - Journal of Heredity, 2024 - academic.oup.com
Multicopy sequences evolve adaptations for increasing their copy number within nuclei. The
activities of multicopy sequences under constraints imposed by cellular and organismal …
activities of multicopy sequences under constraints imposed by cellular and organismal …
Assessing Human Ribosomal DNA Variation and Its Association With Phenotypic Outcomes
F Rodriguez‐Algarra, E Whittaker… - …, 2025 - Wiley Online Library
Although genome‐scale analyses have provided insights into the connection between
genetic variability and complex human phenotypes, much trait variation is still not fully …
genetic variability and complex human phenotypes, much trait variation is still not fully …
[HTML][HTML] Copy Number Variations of Human Ribosomal Genes in Health and Disease: Role and Causes
NN Veiko, ES Ershova, EI Kondratyeva… - Frontiers in Bioscience …, 2025 - imrpress.com
Background: A number of association studies have linked ribosomal DNA gene copy
number (rDNA CN) to aging and pathology. Data from these studies are contradictory and …
number (rDNA CN) to aging and pathology. Data from these studies are contradictory and …
A groundbreaking achievement in genomics: the complete telomere-to-telomere sequence of a mouse genome
WG Zhu - Genome Instability & Disease, 2025 - Springer
Abstract The article titled “The Complete telomere-to-telomere Sequence of a Mouse
Genome” provides a significant advancement in the field of genomics by completing the …
Genome” provides a significant advancement in the field of genomics by completing the …