Although carbon is the central element of organic chemistry, oxygen is the central element of
stereoelectronic control in organic chemistry. Generally, a molecule with a C–O bond has …

Excessive inflammation, bacterial infection, and blocked angiogenesis make diabetic wound
healing challenging. Multifunctional wound dressings have several advantages in diabetic …

Despite continuing advances in the development of biomacromolecules for therapeutic
purposes, successful application of these often large and hydrophilic molecules has been …

The molecular conformation of the carboxyl group can be crucial for its chemical properties
and intermolecular interactions, especially in complex molecular environments such as …

The shape of eukaryotic cells is determined by the cytoskeleton associated with membrane
proteins; however, the detailed mechanism of how the integral morphologies with structural …

The pH low insertion peptide (pHLIP) is a pH-sensitive cell penetrating peptide that
transforms from an unstructured coil on the membrane surface at pH> 7, to a transmembrane …

Over the past two decades, gene therapy, as a promising way to regulate or replace
abnormal gene, has made impressive progress with numerous clinic trials. However, the …

Cancer, being the most prevalent and resistant disease afflicting any gender, age or social
status, is the ultimate challenge for the scientific community. The new generation …

Cancerous tissues undergo extensive changes to their cellular environments that
differentiate them from healthy tissues. These changes include changes in extracellular pH …

Many important biological pathways rely on membrane-interacting peptides or proteins,
which can alter the biophysical properties of the cell membrane by simply adsorbing to its …