Aldosterone is a steroid hormone synthesized in and secreted from the outer layer of the
adrenal cortex, the zona glomerulosa. Aldosterone is responsible for regulating sodium …

Lysophosphatidic acid (LPA, 1-or 2-acyl-sn-glycerol 3-phosphate) mediates a plethora of
physiological and pathological activities via interactions with a series of high affinity G …

Gonadal steroid production is stimulated by gonadotropin binding to G protein-coupled
receptors (GPCRs). Although GPCR-mediated increases in intracellular cAMP are known …

We have demonstrated earlier that lysophosphatidic acid (LPA)-induced interleukin-8 (IL-8)
secretion is regulated by protein kinase Cδ (PKCδ)-dependent NF-κB activation in human …

The V2 vasopressin receptor (V2R) activates the mitogen activated protein kinases (MAPK)
ERK1/2 through a mechanism involving the scaffolding protein βarrestin. Here we report that …

Lysophosphatidic acid (LPA), a potent bioactive phospholipid, induces diverse cellular
responses, including cell proliferation, migration, and cytokine release. LPA can be …

Two well-known protein complexes in mammalian cells, mTOR type 1 and type 2
(mTORC1/2) are involved in several cellular processes such as protein synthesis, cell …

Lysophosphatidic acid (LPA) is a bioactive phospholipids and involves in various cellular
events, including tumor cell migration. In the present study, we investigated LPA receptor …

Context: Differential methylation of CpG regions is the best-defined mechanism of epigenetic
regulation of gene expression. Objective: Our objective was to determine whether any …

Background: Parathyroid carcinoma (PCa) is rare and often difficult to differentiate initially
from benign disease. Because PCa oversecretes amino PTH that is detected by third …