Visible-to-NIR-light activated release: from small molecules to nanomaterials
Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …
Progress in the development of human carbonic anhydrase inhibitors and their pharmacological applications: Where are we today?
CB Mishra, M Tiwari, CT Supuran - Medicinal Research …, 2020 - Wiley Online Library
Abstract Carbonic anhydrases (CAs, EC 4.2. 1.1) are widely distributed metalloenzymes in
both prokaryotes and eukaryotes. They efficiently catalyze the reversible hydration of carbon …
both prokaryotes and eukaryotes. They efficiently catalyze the reversible hydration of carbon …
Discovery of novel benzenesulfonamides incorporating 1, 2, 3-triazole scaffold as carbonic anhydrase I, II, IX, and XII inhibitors
Sulfonamides are among the most promising potential inhibitors for carbonic anhydrases
(CAs), which are pharmaceutically relevant targets for treating several disease conditions …
(CAs), which are pharmaceutically relevant targets for treating several disease conditions …
How many carbonic anhydrase inhibition mechanisms exist?
CT Supuran - Journal of enzyme inhibition and medicinal chemistry, 2016 - Taylor & Francis
Six genetic families of the enzyme carbonic anhydrase (CA, EC 4.2. 1.1) were described to
date. Inhibition of CAs has pharmacologic applications in the field of antiglaucoma …
date. Inhibition of CAs has pharmacologic applications in the field of antiglaucoma …
Multiple binding modes of inhibitors to carbonic anhydrases: how to design specific drugs targeting 15 different isoforms?
V Alterio, A Di Fiore, K D'Ambrosio, CT Supuran… - Chemical …, 2012 - ACS Publications
Carbonic anhydrases (CAs, EC 4.2. 1.1) are ubiquitous metallo-enzymes, present
throughout most living organisms and encoded by five evolutionarily unrelated gene …
throughout most living organisms and encoded by five evolutionarily unrelated gene …
1, 3, 4-Thiadiazole: synthesis, reactions, and applications in medicinal, agricultural, and materials chemistry
Y Hu, CY Li, XM Wang, YH Yang, HL Zhu - Chemical reviews, 2014 - ACS Publications
Over the past decades, the bulk of chemists' interests have been on heterocyclic compounds
and their various derivatives as well as their applications in the pharmaceutical and …
and their various derivatives as well as their applications in the pharmaceutical and …
Recent advances in the medicinal chemistry of carbonic anhydrase inhibitors
Abstract Carbonic anhydrase (CA, EC 4.2. 1.1) is an enzyme and a very omnipresent zinc
metalloenzyme which catalyzed the reversible hydration and dehydration of carbon dioxide …
metalloenzyme which catalyzed the reversible hydration and dehydration of carbon dioxide …
Structure-based drug discovery of carbonic anhydrase inhibitors
CT Supuran - Journal of enzyme inhibition and medicinal chemistry, 2012 - Taylor & Francis
Inhibition of the metalloenzyme carbonic anhydrase (CA; EC 4.2. 1.1) has pharmacologic
applications in the field of anti-glaucoma, anti-convulsant and anti-cancer agents. But …
applications in the field of anti-glaucoma, anti-convulsant and anti-cancer agents. But …
Carbonic anhydrase inhibitors
CT Supuran - Bioorganic & medicinal chemistry letters, 2010 - Elsevier
Carbonic anhydrases (CAs, EC 4.2. 1.1) are widespread enzymes in all organisms,
catalyzing CO2 hydration to bicarbonate and protons. Their inhibition is exploited clinically …
catalyzing CO2 hydration to bicarbonate and protons. Their inhibition is exploited clinically …
Coral calcification, cells to reefs
D Allemand, É Tambutté, D Zoccola… - Coral reefs: an ecosystem …, 2011 - Springer
In spite of more than one century and half of studies, mechanisms of coral biomineralization,
leading to coral growth and reef formation, still remain poorly known, although major global …
leading to coral growth and reef formation, still remain poorly known, although major global …